Experiences with

Enzalutamide

Amazing journey. will try enzalutamide when things get out of hand. also have in mind lutetium 177 which I will have to pay for. Izab Izab

Interestingly, he says that "I do not endorse giving both abiraterone and enzalutamide." I wonder why? -Patrick [1] https://www.medscape.com/viewarticle/888466

Management of Anticoagulation in Patients With Prostate Cancer Receiving Enzalutamide. Shatzel JJ1, Daughety MM1, Olson SR1, Beer TM1, DeLoughery TG1.

I have been given 3 options which are Cabazitaxel, Abiraterone or Enzalutamide!

Been on Lupron for two years and also on enzalutamide for a year (as part of a study that includes a new immunotherapy). seriously considering just quitting treating. i'm 55 and this sucks so much more than any of my friends and family know.

"Much less is known about the timing and interaction between radium 223 and the newer antiandrogen agents (abiraterone or enzalutamide).

I know Abiraterone and enzalutamide are in my future, but I'm reaching out for thoughts and comments.

https://www.urotoday.com/recent-abstracts/urologic-oncology/prostate-cancer/99108-prosper-trial-results-of-enzalutamide-in-non-metastatic-castration-resistant-prostate-cancer.html Gus

Patients with evidence of progression on enzalutamide were treated with pembrolizumab 200 mg IV every 3 weeks for 4 doses; pembrolizumab was added to standard dose enzalutamide.

Concomitant agents were allowed at investigator discretion, excluding chemotherapy and initiation of new abiraterone or enzalutamide.

In a clinical study of enzalutamide for ER-positive breast cancer in women, enzalutamide was found to decrease serum concentrations of the aromatase inhibitors anastrozole and exemestane by 90% and 50%, respectively, which could reduce their effectiveness." [3] " Enzalutamide is the only oral chemotherapeutic

Since then my PSA has been creeping up and with it now at 2.28 I have just been prescribed Enzalutamide.

By using C4-2, CWR22Rv1 and LNCaP cell lines, as well as mice bearing CWR22Rv1 xenografts treated with either enzalutamide or metformin alone or in combination, we demonstrated that metformin is capable of reversing enzalutamide resistance and restores sensitivity of CWR22Rv1 xenografts to enzalutamide

I've been on a 160 mg dose for three months now and while my PSA dropped dramatically, the fatigue is just crippling. I'm 59 with a senior management job, honestly not sure how I can keep going and I certainly can't afford to retire much as I'd like to! I find myself taking 1-2 sick days regularly just

Moreover, it can also determine whether or not the tumor is resistant to treatment with abiraterone and enzalutamide.

All were treated with enzalutamide (35%), abiraterone (6%) or both (59%). Most were ECOG status 0-1. 63% had bony and visceral metastatic disease.

Please tell me what you know about Enzalutamide without copy+pasting from a website. I am so scared for my dad as he just found out his prostate cancer has now metastasized to his bones. What are your personal experiences and what should I expect from here on out?

So, the usefulness of the test really becomes important after abiraterone or enzalutamide particularly. The second AR-V7 test, which was developed at Johns Hopkins by Dr. Luo’s lab, is an RNA-based expression.

The role of the androgen receptor (AR) was investigated using the AR antagonist, Enzalutamide. The combination of MET and VPA synergistically inhibited proliferation in LNCaP and PC-3, with no significant effect in PrEC.

He will be starting Enzalutamide in a few weeks. Needless to say I am feeling so many emotions including anger and sadness. I don't want my Dad to die. I'm 28 years old and not sure what I'm going to do without him!