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Enzalutamide
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AR-V7
"The purpose of this study is to compare galeterone to
enzalutamide
in men expressing androgen receptor spice variant-7 mRNA (AR-V7) in metastatic (M1) castrate resistant prostate cancer (CRPC).
"The purpose of this study is to compare galeterone to
enzalutamide
in men expressing androgen receptor spice variant-7 mRNA (AR-V7) in metastatic (M1) castrate resistant prostate cancer (CRPC).
pjoshea13
in
Advanced Prostate Cancer
8 years ago
Glenn from mississauga ont canada with advanced prostate cancer
- 2011 bang advanced prostate cancer out of the blue at 54 - gleason 9.5 mets to hips and spine, in lympnodes - tried most things zoledex, abiraterone (Zytiga®), Docetaxel (Taxotere®) Cabazitaxel (Jevtana®), radium 223,
Enzalutamide
, xgeva,zometa, - on my 3rd round of chemo Docetaxel and Carbplatin
- 2011 bang advanced prostate cancer out of the blue at 54 - gleason 9.5 mets to hips and spine, in lympnodes - tried most things zoledex, abiraterone (Zytiga®), Docetaxel (Taxotere®) Cabazitaxel (Jevtana®), radium 223,
Enzalutamide
, xgeva,zometa, - on my 3rd round of chemo Docetaxel and Carbplatin
glennporemba
in
Advanced Prostate Cancer
8 years ago
Significance of early PSA response.
KEYWORDS: Abiraterone;
Enzalutamide
; PSA; Prostate cancer PMID: 27151554 [PubMed - as supplied by publisher]
KEYWORDS: Abiraterone;
Enzalutamide
; PSA; Prostate cancer PMID: 27151554 [PubMed - as supplied by publisher]
pjoshea13
in
Advanced Prostate Cancer
8 years ago
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New here, diagnosed age 52, Gleason 10
. -09/25/2013- ADT started (Lupron) -02/5/14- started MDV3100-09 (STRIVE): A Multicenter Phase 2, Randomized, Double-Blind, Efficacy and Safety Study of
Enzalutamide
vs.
. -09/25/2013- ADT started (Lupron) -02/5/14- started MDV3100-09 (STRIVE): A Multicenter Phase 2, Randomized, Double-Blind, Efficacy and Safety Study of
Enzalutamide
vs.
Glsn10
in
Advanced Prostate Cancer
8 years ago
Retinoic acid receptor–related orphan receptor γ (ROR-γ) & the Androgen Receptor (AR)
"ROR-γ antagonists suppressed tumor growth in multiple AR-expressing, but not AR-negative, xenograft PCa models, and they effectively sensitized CRPC tumors to
enzalutamide
, without overt toxicity, in mice."
"ROR-γ antagonists suppressed tumor growth in multiple AR-expressing, but not AR-negative, xenograft PCa models, and they effectively sensitized CRPC tumors to
enzalutamide
, without overt toxicity, in mice."
pjoshea13
in
Advanced Prostate Cancer
8 years ago
Metatstatic PCA to lymphs, bones & lung
Enzalutamide
has brought his PSA down to 15, the lowest that it has been for 5 years. He is now on a bit of a plateau. I have read a bit about Metformin and wondered if this was possibly something that could be added. Any comments/ observation would be most welkcome. Thanks, Carol2
Enzalutamide
has brought his PSA down to 15, the lowest that it has been for 5 years. He is now on a bit of a plateau. I have read a bit about Metformin and wondered if this was possibly something that could be added. Any comments/ observation would be most welkcome. Thanks, Carol2
Carol2
in
Advanced Prostate Cancer
8 years ago
Xtandi ?
Cost of Xtandi (
enzalutamide
) Diagnosed in 2000 at age 61. PSA 5.6. Radical retropubic prostatectomy. Detectable PSA 18 months post surgery. Salvage radiation 2003. PSA has continued to rise almost continuously to current level – 197.8.
Cost of Xtandi (
enzalutamide
) Diagnosed in 2000 at age 61. PSA 5.6. Radical retropubic prostatectomy. Detectable PSA 18 months post surgery. Salvage radiation 2003. PSA has continued to rise almost continuously to current level – 197.8.
Davisjl
in
Advanced Prostate Cancer
8 years ago
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