Experiences with

Afatinib

Over the past 2 years I have had Afatinib, immunotherapy, chemotherapy and a trial drug which had a code type name. Happy to pass on names of drugs if anyone wants them.

Anyway I’m still taking afatinib and will wait to see what my blood biopsy shows to see where I go from now Stay safe

Hi Iv been on 50mg afatinib now for 14 months though I struggle with the rash Iv got antibiotics if it gets too bad just wondering if if ever settles on it’s own

https://en.wikipedia.org/wiki/Quinazolinone Other Quinazoline-Containing Drugs: -- for treatment of cancers resistant to gefinitib and erlotinib. -- Erlotinib, an anti-tumor agent. -- Lapatinib for treatment of advanced-stage or metastatic breast cancer.

I was diagnosed with stage 4 lung cancer in early 2020 and was given the targeted therapy Afatinib. This was initially most effective but gradually stopped working and so the cancer spread further in the lungs.

Previously, I posted on the topic of cellular senescence, "zomby-like" cells that cannot divide but also do not die. They can become SASP cells, Senscent-Associated Secretory Phenotypes, that can promote the growth and progression of processes in other cells, including PC cells by secreting pro-inflammatory

Hi there Can anybody recommend a makeup that is suitable for rash prone skin I am on afatinib 50mg and have a red face at the moment 🙈though I won’t wear anything while I have it but after it’s gone I would like to get some slap on.

Hi I’m on afatinib 50mg have been ok but Iv got a rash on my face nose is blocked and eyebrows all dried up I look like Iv be burned any ideas how to relieve would be appreciated

I was interested to see in the latest from the Mayo: "Antidiabetic Effects of the Senolytic Agent Dasatinib" [1] Many men with PCa are pre-diabetic at diagnosis, with some of the symptons of the metabolic syndrome [MetS]. Pre-diabetics do not necessarily progress to diabetes, but androgen deprivation

Nalakrats has in two major posts shared fascinating insights on senescence and senolytics, drugs that selectively clear senescent cells. I am most grateful to him for this, which set me off on a journey the results of which I sum up in this post. Senescence has also recently been well reported on by

Hidden clued me into quercetin and fisetin, And LAJ12345 just had quercetin on their list of Mucoactive natural products https://healthunlocked.com/cure-parkinsons/posts/146670689/mucoactive-natural-products and laglag and SilentEchoes had some great information at https://healthunlocked.com/cure-parkinsons

FYI - Inhibikase Therapeutics (IKT) is taking a stab at PD. https://finance.yahoo.com/news/inhibikase-initiates-early-stage-study-174801680.html Vandana Singh February 17, 2021 Inhibikase Therapeutics Inc (NASDAQ: IKT) has dosed the first patients in its Phase 1 trial of IkT-148009, an Abelson

NSCLung cancer changing to small cell.

Hi, Has anyone taken Candilap? Anyone who knows about or has taken Lapatinib?

Hi I was diagnosed with stage 4 lung cancer in February and I am now taking afatinib and the tumour has shrunk thank goodness tho now after all this time my arms and stomach have broke out in the “rash” I was told to plaster myself in cetriban but was wondering does anybody have any tips

Link below says that it is to be used "for disease without the KIT[D816V] mutation". https://www.nice.org.uk/guidance/gid-ta10503/documents/final-scope https://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=EN&Expert=98850

Did this for 3 reasons. I am one of a handful of around 20 people taking both drugs with rux maybe one of 10 taking it with with a trial drug as well. Why do I do it? Other patients took the gamble to try rux and imatinib and lost their gamble so I feel I owe my opportunity to them. Pure research. This

You can all see my post from 2 or so weeks ago. I knew shortly after my iron levels were elevated due to transfusions. Ferritin is also an inflammatory marker but my total iron combining capacity has also been rising steadily ( TIBC). I cannot reduce my transfusion dependency as I have gone down to 52

All in all I feel OK will be happier once they restart my Afatinib but until then I just keep chugging on. I have a very talkative dog and cat that keep me company. :)

This is a follow up to my quest to prevent BCR's and to maim/inactivate sleeping cancer cells, for those men who reach PSA Undetectability with clean scans. There is an underlying theme thru some of my posts that says--->when the treatments stop, it is time to treat. Yes some men continue to treat with