Is there a cream which can be applied to lesions caused by Sweet's Syndrome , other than Cortico Steroid applications?

[Ginna]

[Shell567 Administrator Sweet's Syndrome UK]

Hi Ginna, unfortunately not. There is a cream called Pimecrolimus that is used as an alternative to steroid cream in the treatment of conditions such as eczema, but it's never been trialled as a treatment for SS lesions.

If your lesions are large, or your SS keeps flaring up, you really need oral medication. Also, be careful about using steroid creams on the face. In the longer term, this can lead to problems such as thinning of the skin and permanent skin discolouration.

Pimecrolimus (DermNet NZ): dermnetnz.org/treatments/pi...

[jerrybelle]

I agree, Sweets needs to be treated from within. I didn't have any luck with Cortico Steroid creams in conjunction with my oral meds, I found it made my lesions more fiery and when they healed the scars were a darker colour than lesions I hadn't used it on, but everyone's reaction is different. After unsuccessfully trying many creams and lotions, Ive settled on raw Shea Butter, it's been my best friend for the last year, it keeps the affected area well moisturized while it soothes. It must be raw, not refined and a word of CAUTION it may cause reactions in people with nut allergies. Jo

[Shell567 Administrator Sweet's Syndrome UK]

Hi notsosweets, there's no literature relating to this, but Lidocaine and Doxepin can't be used as alternatives to steroid cream as they don't have an anti-inflammatory effect. Doxepin is used to help relieve itching, and Lidocaine is a local anaesthetic that can help relieve the itching, pain and burning of skin lesions.