Anyone have experience with this Center
Looks like they are using genetic testing and immuno therapies to treat hormone sensitive Stage 4 Prostate Cancer
Anyone have experience with this Center
Looks like they are using genetic testing and immuno therapies to treat hormone sensitive Stage 4 Prostate Cancer
Did we have this question before but it was deleted? I believed immunotherapy is not needed if your cancer is still hormone sensitive. Immunotherapy sounds great but it may be toxic?
"Immunotherapy sounds great but it may be toxic?"
Please explain
I don't need it at this stage where I am now 5 years after my diagnosis. I am interested in immunotherapy and I am considering it but it lucks like it is still in infancy. Don't jump on something just because it sounds good. I did some investigation about joining AMG 509 but decided it is not for me at this stage. I believe they are not really recommended until we are hormone sensitive. If you known any immunotherapy which is effective and none toxic than please let me know as I am interested.
I know a member with a very aggressive cancer but he believed that keytruda is toxic for him at this stage. I personally lost my hope that there is a magic immunotherapy bullet for the hormone sensitive csncer. My Degarelix just works fine for 5 years and I don't even want to know at this stage my genetic testing results. I hope ADT will work for long. My only real problem with ADT is osteoporosis. I trying to run everyday at list 200m. I just hope that I will not fall.
Let me know which immunotherapy would you recommend for hormone sensitive prostate cancer and I will case by case consider it for myself.
Must admit that my memory of this is vague, can I plead to ADT use?
It worked for me with early chemotherapy. I am polymetastatic in my bones.
For newly diagnosed mHSPC the standard of care is triple therapy:
ADT plus early chemotherapy plus darolutamide (Nubeqa). 63 % of people survived 4 years after starting ADT with triple therapy.
For mCRPC the median survival is 4 years with AAP plus Olaparib according to the PROPEL clinical trial.
It is like winning the lottery.
What exactly are they doing that you find so interesting?
That others are not doing?
Looks like their marketing piece is targeted to a lot of the things we discuss here:
Precision-Targeted Care to Overcome Treatment Failure
Advanced N-of-1 Clinical Trials
Precision Oncology to Counter Metastasis
Advanced Customized Immunotherapy for All Stages and Types of Cancer
Alternatives to Invasive Surgeries
Reduced Risk of Treatment Side Effects
Such as fatigue, nausea, skin rashes, cardiac toxicities, infertility, hair loss, and nerve damage.
Success in All Stages and Types of Cancer
In our 20 years of precision oncology practice, we have successfully treated several complex and metastatic cancers including prostate cancers, lung cancers, breast cancers, colon cancers, lymphomas, and even the rare and complicated glioblastomas and neuroendocrine carcinomas.
Precision-Targeted Care to Overcome Treatment Failure
Like no other time in history, we have more options and targeted technologies to make the best cancer treatment plan, which is comprehensive enough to check failures. These advancements can be beneficial for the patients who have exhausted previous standard treatment options and even alternative therapies, with no success. Both of these aspects of medical care have to be precision-targeted to each patient's unique cancer expressions, for minimizing the risk of chemotherapeutic drug resistance, one of the potential side effects of cancer treatment.
Chemotherapeutic drug resistance is believed to cause treatment failure in over 90% of patients with metastatic cancer.
Longley DB, Johnston PG. Molecular mechanisms of drug resistance. J Pathol. 2005;205(2):275–92.
What is Chemotherapeutic Drug Resistance?
Chemotherapeutic drug resistance, also known as multidrug resistance (MDR), is the result of multiple rounds of untargeted chemotherapy being administered without the cancer responding to the treatment. The cancer cell’s ability to reduce the intake of chemotherapy drugs while at the same time activating its ability to push out the hazardous drugs that have entered the cell, is responsible for the development of resistance to chemotherapy.
Learn more about Chemotherapeutic Drug Resistance
Pgp pumping chemotherapy drugs out of a cancer cell
Cancer Cell Pumping Out Untargeted Chemotherapy Drugs
Advanced N-of-1 Clinical Trials
At Envita, we follow the N-of-1 treatment model, which is a single-subject clinical trial designed to personalize a medical blueprint for each individual patient, improving their chances of response to treatment. This approach of custom-building an entire treatment plan is in direct contrast with standard oncology, where a suitable treatment is sought from the existing pool of options, based on cancer type and stage.
You may be asking yourself, “Why aren’t all cancer centers using precision for everyone?”
Envita Medical Centers building
In our 20 years of clinical experience, we find that custom building a medical blueprint for each patient provides precision treatment options, which help to avoid multidrug resistance in early cases of cancer and overcome it in late-stage cancer cases as well.
Envita Medical Centers building
According to the NCCN (National Comprehensive Cancer Network) guidelines, which drive standard oncology, a patient is treated based on their cancer type and stage. If the standardized medical treatment fails numerous times, then the patient becomes eligible for genomic analysis to identify precision treatment targets.
Our clinical experience proves how crucial an extensive genomic analysis is to understand your specific cancer cell mutations which drive treatment. This detailed analysis is the first step towards precision oncology, but not everyone has access to it in the standard model of cancer care.
They have a very extensive website and the few hyperthreads I followed were to old papers 2005 and 2012 so seems bit like using every buzz word out there to market itself. That said I don't see anything wrong in that but doubt they have anything to offer that can'tbe gotten elsewhere just have it in 1 facility. It seems like a place you could get Vitamin C IV , Chemotherapy and a coffee enema in the same place. But thats just based off the website so no idea if thats accurate. For me it would be out of pocket so not even worth investigating seriously unless they offered LU177 which I saw no mention of in my brief review. I would rather seek opinions from qualified Prostate Specialists and have them correspond with my local Drs for the treatments. Just my opinion.
Keytruda worked on my Melanoma lung metastasis..........
j-o-h-n <===<<< Senior management is about to spike my spikes....
Good Luck, Good Health and Good Humor.
j-o-h-n Tuesday 04/18/2023 6:43 PM DST