Jonathan Epstein on Gleason 6

[dentaltwin]

Given how often Epstein's name comes up here, thought this would be of interest. If folks don't have a Medpage account I can post the text:

medpagetoday.com/reading-ro...

[Tall_Allen]

Here's the other side of the argument from a decade ago:

sciencedirect.com/science/a...

Another roadblock to renaming are IRBs. They will not allow hospitals to rename or even test the hypothesis via RCT until there is evidence of non-inferiority. And without an RCT, it is impossible to get that evidence.

There was a hypothetical survey (asking well men to imagine how they would react), but hypotheticals don't necessarily predict what they would really do:

acsjournals.onlinelibrary.w...

[dentaltwin in reply to Tall_Allen]

Sure, and given the debacle after the 2021 USPSTF statement giving a "D" to PSA screening, I can certainly understand why those who might otherwise undertake a study are gun-shy. I know there are similar issues with DCIS in breast cancer and in papillary thyroid cancer, though I can't remember nearly the same amount of screaming and hair pulling (but maybe that's because I'm not so close to those other dubious "cancers").

[Murk in reply to Tall_Allen]

Anything ten years old is old, I look forward to the debate and progress

[Tall_Allen in reply to Murk]

It's an old debate, and nothing has changed.