Are there any documented cases of post RP uPSA values rising and then plateauing indefinitely at a low level (for instance 0.010 to 0.020)?

[jronne]

Often the subjective consensus is that these rising low uPSA values are no risk or low risk but this view is just state and never backed by any hard data or research.

I have had several friends with low risk clean margin post RP pathology like mine with low rising uPSA values that have been forced to undergo SRT after a few years.

I would like to learn of any other outcome experience.

[julianc]

In UK the advice seems to be to wait until it's higher ... At least 0.1 and more likely 0.2. I've been around 0.05 for 2.5 years, and 5 years post RP. From reading around, I plan to act if I get close to 0.1, as reaching this level means it's highly likely to get to 0.2.

[jronne in reply to julianc]

thx, best wishes

the old school is 0.1 and 0.2. 0.1 is sometimes now considered late as some institutions in the USA are using 2 "substantial" uPSA rises spaced 3 months apart being 6 months total. my friend got SRT at uPSA of 0.045. 60 years old preceded by 3 months of ADT.

what is you uPSA history ?

do you have a doubling time?

what was your pathology?

btw uPSA is the best test because other tests fail close to their lower limits