PIPAC

[Reksio77]

Hello ladies. Do you have any experience with so called "PIPAC" procedure (pressurized intraperitoneal aerosol chemotherapy)?

[Lyndy2]

No never heard of it! Do tell us what you know? x

[Reksio77 in reply to Lyndy2]

Below one of the quotes I've found: "Ovarian cancer has a high recurrence rate, with most cases being peritoneal metastasis. The standard treatment of peritoneal metastasis is systemic chemotherapy, but naturally, the peritoneum is poorly vascularized, making this standard of treatment frequently ineffective. Hence, pressurized intraperitoneal aerosol chemotherapy (PIPAC) introduced a new type of intraperitoneal chemotherapy (IPC) in November 2011. Positive feedback on its feasibility, tolerance, and efficacy has encouraged medical communities worldwide to adopt PIPAC as a new drug delivery technique." I'm sure that PIPAC method is known in UK.

[Lovedogs41]

Hi

I think it’s called Hipec it’s heated chemo put directly into the abdomen rather than iv chemo I believe.It’s meant to be more effective at getting to peritoneal metastasis.It is available in the UK but not widely.

[Reksio77 in reply to Lovedogs41]

PIPAC and HIPEC are not the same. PIPAC = Pressurized intraperitoneal aerosol chemotherapy. HIPEC = hyperthermic intraperitoneal chemotherapy. HIPEC especially involves major surgery to remove most if not all the visible cancers in the abdomen, while PIPAC is less invasive than HIPEC as it is delivered laparoscopically. In Switzerland both methodes are used. Will have a CT next week and if my cancer's lesions are still and only on peritoneum I will try to qualify for PIPAC procedure.

[Lyndy2]

We are learning a lot! Thanks for sharing Reksio77 but atm looks like you are the expert! xx

[ruthg55]

Hi Reksio,

I don't have experience with the one you are talking about, but I did have interperitoneal chemo plus IV chemo 7 years ago. The IP I had was given through a port in my abdomen. It involved an overnight stay in hospital because you are given a lot of fluid intravenously to flush out your kidneys. It was much heavier treatment than IV, but still doable although I stopped the IP (my decision) after 3 sessions instead of 6 sessions, but continued with the IV. I'm in Australia and they only give you IP if there is nothing visible after debulking surgery or if there is, it has to be less than 2cms otherwise they don't see any benefit in having this harsher chemo. Wishing you all the best!