has anyone experienced neuropathy as a result of rituximab

[PossumPracticalCat]

Has anyone experienced neuropathy as a result of rituximab for non hodgkins lymphoma

[Name-1]

I received R 6 cycles and I have neuropathie in my leggs.

[81ue]

I had a pins and needles feeling that made hugs painful and it went away eventually. It lasted a few weeks.

[BerkshireBear in reply to 81ue]

According to the Neurologists treating me, almost any drug or chemical can be a trigger to neuropathy in the right individual. In other words, it could happen. When I was treated with the cocktail R-CHOP and follow-up maintenance with Rituximab my oncologist specifically removed one item from the cocktail because I already had neuropathy and he said that item was known to trigger or worsen the PN. That item was the "O" Vincristine sulfate (Oncovin). But as my neurologists say, almost anything might be the culprit in a specific body. I don't think we will ever really know.

[Nusch in reply to BerkshireBear]

Same for me. Vincristine was replaced by Etoposide in R-CHOP therapy.

[PeterP54 in reply to BerkshireBear]

I started to lose sensation in the toes of my right foot. I was being treated with R-CHOP and the vincritine element was removed from my regime. Now, 11 years on i barely notice it.

[Lizard28]

I was the same, you have to tell them about it. I had R-CVP, the cocktail that caused the problem was the vincristine, they had to cut it down , it affected my fingers and toes.

[LarryK]

From the web: Side effects of vincristine:

- numbness or tingling in fingers and toes

- pain in fingers and toes

-neuritic pain

These effects are generally reversible when medication ceases.

Side effects of Rituximab from Mayo Clinic. One of the many (50) side effects was numbness or timgling of hands, toes, or lips mayoclinic.org/drugs-supple...

[sparklesbw]

Yes, I did experience neuropathy after Rituximab and I still have it on the bottom of my feet, 11years after taking rituximab with bendamustine during 4 months of the chemo for non hodgkin lymphoma.

I take gabapentin, which I don’t think helps, much, and more recently used lidocaine cream (gotten over the counter or prescription) (please read the label)

I hope I’ve helped.

Barb