Someone last week was talking about how the FDA had increased the dose of the 2 injections we receive of Evusheld. It was 150 mg of each and now it has been raised to 2 injections of 300 mg. So I will be going today to receive my additional doses. My doctor sent me the following, if you want to contact your PCP/Nephrologist.
[2/24/2022] The U.S. Food and Drug Administration has revised the emergency use authorization for Evusheld (tixagevimab co-packaged with cilgavimab) to change the initial dose for the authorized use as pre-exposure prophylaxis (prevention) of COVID-19 in certain adults and pediatric patients.
Based on the most recent information and data available, Evusheld may be less active against certain Omicron subvariants. The dosing regimen was revised because available data indicate that a higher dose of Evusheld may be more likely to prevent infection by the COVID-19 Omicron subvariants BA.1 and BA.1.1 than the originally authorized Evusheld dose.
Previously, the authorized Evusheld dosage was 150 mg of tixagevimab and 150 mg of cilgavimab administered as two separate consecutive intramuscular injections, with repeat doses every six months while SARS-CoV-2 remains in circulation. With this EUA revision, FDA has increased the initial authorized dose to 300 mg of tixagevimab and 300 mg of cilgavimab. Patients who have already received the previously authorized dose (150 mg of tixagevimab and 150 mg of cilgavimab) should receive an additional dose of 150 mg of tixagevimab and 150 mg of cilgavimab as soon as possible to raise their monoclonal antibody levels to those expected for patients receiving the higher dose.
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WYOAnne
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No. Just the original 2 vaccines and one booster. I got the Evusheld the end of January, the original dose 150 mg tixagevimab and 150 mg cilgavimab. Today I received the same 150 mg or each again. So 6 months from today I will receive 300 mg of tixagevimab and 300 mg of cilgavimab.Hope the FDA doesn't change their mind again! Ha, ha.
I will do what I have to, so I don't get COVID. This new dosage of 300 mg is suppose to offer more protection against Omicron variant.
This is the first I ever heard of it - what exactly is Evusheld? I have had 2 Pfizer shots and a booster of Pfizer last year. I don't believe my transplant nephrologist ever mentioned it.
Evusheld is a preventative for COVID for those of us that are immunosuppressed. Many of us did not build up antibodies or did not have a normal response to the vaccines. Evusheld got "emergency use authorization". It is monoclonal antibodies used as a preventative. It is given as 2 injections and is repeated every 6 months.Makes me feel better about going out to church, the grocery store, etc.
I know my nephrologist was recommended it for all of his patients.
I guess the real question is if you have made antibodies with the vaccine and booster? I know that I did, but there was no way to know how many, was it a normal amount, was it a small amount. I don't think unless you were in a study, can you know for sure the amount, the number of antibodies. That is why my doctor recommended me to get Evusheld.
Hmm, I think I read that the monoclonal antibodies should be used for immunosuppressed patients who contract COVID according to our local hospital system as a way to prevent more severe disease and hospitalization. I also was tested for my antibodies after the shots, but there was no way to tell how many antibodies I had developed. Just the same, I'll ask my nephrologist when I have an appointment this month. He may simply recommend a 4th vaccine.
I am not sure, but I believe the monoclonal antibodies you receive once you are positive for COVID is different than the Evusheld which is a preventative
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