Hereditary?: Research says that MS is not... - My MSAA Community

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Hereditary?

Katypadiddle profile image
31 Replies

Research says that MS is not hereditary but family members have a 2% chance of being affected. What do y’all think?

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Katypadiddle profile image
Katypadiddle
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31 Replies
Sandydemop profile image
Sandydemop

my mother, sister and maternal aunt had MS, as do I. i don't think that's a coincidence.

kdali profile image
kdali

I'm the only autoimmune disease in my family.

Kenu profile image
Kenu in reply to kdali

Me too and was diagnosed at 39 years old.

kdali profile image
kdali in reply to Kenu

We had genetic counseling with our first and I believe their risk was 1% or something. As for me, I was super sick with mono and I think no one else in my gene pool had anything that bad 🤷‍♀️

Sandydemop profile image
Sandydemop in reply to kdali

I had mono in college. they say that might be a risk factor.

Jer29-11 profile image
Jer29-11 in reply to kdali

My sister and I both had mono in high school. She was super sick with it, I was not. I’m the one who ended up with MS. Our maternal grandmother had MS though too. Genetics are weird!

kdali profile image
kdali in reply to Jer29-11

Yes, very weird!

falalalala profile image
falalalala

I'm the only one with MS in my family.

carolek572 profile image
carolek572CommunityAmbassador

Everyone in my immediate family has had cancer, except me, Katypadiddle . I am the only one that has ‘ms’.

Koalagreen profile image
Koalagreen in reply to carolek572

As the mine , the parents of my father had cancer , and the mother of my mother had cancer . But only me with MS. And , What about Royce? Where is Royce, carolek? Is he well?

carolek572 profile image
carolek572CommunityAmbassador in reply to Koalagreen

I, like you, do not know of the well-being of RoyceNewton , Koalagreen . All that I can say is keep him in your thoughts and prayers.

CalfeeChick profile image
CalfeeChickCommunityAmbassador

No one in my family ever had MS. I was worried about Alzheimer's, as my mother and her sister both had that!

Tazmanian profile image
Tazmanian in reply to CalfeeChick

Great you can forget you have MS

NorasMom profile image
NorasMom

I don't know that I think that MS itself is hereditary, but I certainly believe that AI diseases can run in families, and I wish they'd spend more time looking at the specific chromosomes associated with MS. I have MS, my son is undiagnosed but has multiple markers for both Lupus and Rheumatoid Arthritis, my daughter's a Type 1 Diabetic, my grandfather showed definite signs of Myasthenia Gravis, and I had 2 cousins who died of a supposedly-rare childhood cancer. My mother and her sisters have some weird blood and bone disorders, but I don't know if they qualify as AI or not.

Cutefreckles72 profile image
Cutefreckles72

I have 4 cousins on my mother's side of the family that have MS. And now I have it. But my mother didn't have MS I honestly think it's hereditary.

Humbrd profile image
Humbrd

I think it's hereditary. There's me. My older sister had it. And my younger sister shows signs.

Raingrrl profile image
Raingrrl

From the National MS Society:

“Genetic Factors

MS is not an inherited disease, meaning it is not a disease that is passed down from generation to generation. However, in MS there is genetic risk that may be inherited. In the general population, the risk of developing MS is about 1 in 750 - 1000. In identical twins, if one twin has MS the risk that the other twin will develop MS is about 1 in 4. The risk of developing MS is also increased when other first degree relative (parents, siblings and children) have MS, but far less than in identical twins.

About 200 genes have been identified that each contribute a small amount to the overall risk of developing MS. Research is ongoing to better understand genetic risk and other factors that contribute to the development of MS.”

Elizt3 profile image
Elizt3

A mix of genetics and environmental factor (s). It’s not an inherited disease, like Huntington’s disease. I think the risk of developing MS when it’s in the family is somewhere in the range of 3 to 5%? As I was making it through my 20s and approaching my 30s, I thought I was safe. It was something I feared starting in my early teens. My mother had it. At 30, I was diagnosed. Hoping my daughters make it through without it. 🤞🏻

IFwczs profile image
IFwczs

Who determined the 2% probability for your family members to get MS?

Amore55 profile image
Amore55

I truly hope it is not hereditary. I have worried (as I am sure we all have) about our children getting it. One of my sons has Hashimoto’s disease. That’s hard enough to see. My oldest son has had two bouts of testicular cancer and beat them both, by a miracle. Enough! So, please no MS. Good post.

whwiechm profile image
whwiechm

My youngest daughter also has MS. Is it just the northern climate or is it heredity? Who knows.

Katypadiddle profile image
Katypadiddle

It seems to me that people are being diagnosed at an earlier age too. Seems like when I was diagnosed that the age was 50 or older. Is it that we’ve gotten better at understanding the disease and who and how it affects people?

Frances_B profile image
Frances_B in reply to Katypadiddle

Not quite on the ball. MS has always been recognised as a younger person's disease (i.e. mid-20s through to late 30s, and many people over 45 have had trouble getting diagnosed because doctors don't think of MS as a possibility. Now however, there is a higher prevalence of MS diagnosis in older age groups such as the over 50's and above - it's thought that some of this may be due to better diagnostic tests. While it's not extremely common, some people are being diagnosed in their 60s and above.

twooldcrows profile image
twooldcrows

don't know for sure ....

Tazmanian profile image
Tazmanian

No one in my family has MS nor did I have mono but guess what?

Godschild-warrior profile image
Godschild-warrior in reply to Tazmanian

Same and I however I do feel blessed either way. 🙏😀

pamgarner profile image
pamgarner

i think a gene is passed on for auto immune disease.i have a family that is full of different ones,now I am the only one with MS. but i do know of a family the has 8 females and they all have it and so does their mother....hmmmm

greaterexp profile image
greaterexp

I think there is still an awful lot we don't know.

Frances_B profile image
Frances_B

What you are talking about is not heredity but genetic disposition.

An hereditary disease is not the same as a person having a genetic predisposition for a disease. People can be in families where someone in the family has an inherited disease (such as Huntingtons) but have no inherited genes which will cause them to also develop that disease. People can also be members of families where there is a genetic predisposition to some diseases (e.g. heart disease, diabetes) and it's not possible to predict who will develop the disease and who won't. Some genetic predispositions are stronger that others, and in many instances lifestyle and other external factors will influence whether someone develops a disease or not.verywellhealth.com/genetic-...

medlineplus.gov/genetics/un...

emedicinehealth.com/types_a...

MS is not an inherited disease, but there can be a genetic predisposition. It's best to get the difference clear in your mind so that you don't confuse or mislead other people if/when talking about the topic.

Jeaniem130 profile image
Jeaniem130

My husbands mother and sister have ms, and an uncle on his dad's side. My husband had an issue that occurred a few months ago that concerns me but he ignored it.

BlanketTime1 profile image
BlanketTime1

i think until researchers know all of the causes of an illness or disease, they shouldn't claim anything absolutely. there are too many occurrences where multiple family members have ms to say that categorically imo.