I am continuing my effort to document all the good things Sulforaphane can do for us.
There is a lot of formatting, so the entire post is on my blog: Sulforaphane may activate certain genes that protect cells against oxidative stress, inflammation, and DNA-damage rbd-pd-protocols.blogspot.c...
This is my takeaway portion of the post:
My key takeaways are (my [Dave the high school graduate] takeaways):
• Sulforaphane counteracts many of the same biochemical and molecular abnormalities associated with ASD, including oxidative stress and reduced antioxidant capacity, defects in glutathione synthesis, mitochondrial dysfunction and low oxidative phosphorylation, increased lipid peroxidation, and neuroinflammation.
• Sulforaphane can ameliorate a number of unrelated genetic disorders by activating the “stress proteome".
• Sulforaphane has been shown in vitro to have therapeutic potential to reestablish cellular homeostasis in a number of unrelated genetic disorders.
• Sulforaphane is considered to be of low toxicity, and its administration to humans is well tolerated.
• Fever up-regulates heat-shock proteins and related mechanisms central to multiple cellular processes in the CNS, including synaptic transmission, and may improve long-range cerebral cortical connectivity that is depressed in ASD. Sulforaphane also up-regulates expression of the heat-shock response.
• The participants in the trial generally improved with daily sulforaphane treatment up to week 18. At week 18 they discontinued the treatment and the participants scores returned to baseline. This tells me this sulforaphane treatment needs to be continued to be effective. Maybe instead of trying to slay the dragon, we need to work at taming the dragon?
• I have a high school degree. Caveat Emptor.
Dave
