The MRIgFUS lesion shrinks. Who knew? - Cure Parkinson's

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The MRIgFUS lesion shrinks. Who knew?

MBAnderson profile image
10 Replies

That explains a lot.

" These lesions then shrink over time most likely due to scarring, and in humans, these lesions reach a plateau around 6 months after the RF91 and 3 months after the MRIgFUS interventions.65 92 93"

jnnp.bmj.com/content/89/7/7...

jnnp.bmj.com/content/89/7/727

researchgate.net/publicatio...

(You can find a blow up of this graph in the link.)

jnnp.bmj.com/content/jnnp/8...

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MBAnderson profile image
MBAnderson
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10 Replies
park_bear profile image
park_bear

I wonder if the lesion shrinkage is due to the dead cells that got zapped being cleared out. Their function would not necessarily have been replaced.

MBAnderson profile image
MBAnderson in reply to park_bear

I am looking for the explanation

rebtar profile image
rebtar

Mark, could you explain for those of us who have some trouble understanding the clinical trial documents, what is important about this information?

MBAnderson profile image
MBAnderson in reply to rebtar

It might explain why if (or that) some symptoms might partially return after the FUS surgery.

Juliegrace profile image
Juliegrace

I knew this based on my experience. Or, at least. I am convinced this is what happened to me.

Trixiedee profile image
Trixiedee in reply to Juliegrace

Where and when did you have FUS?

Juliegrace profile image
Juliegrace in reply to Trixiedee

2016 in Baltimore as part of the research study for FUS pallidotomy. I’ve posted about it in the past.

MBAnderson profile image
MBAnderson in reply to Juliegrace

How satisfied are you with it?

Juliegrace profile image
Juliegrace in reply to MBAnderson

Not very as it did not last very long (4-6 months). My theory is that initially the lesion was bigger and there was swelling that gave me a better result, but as the lesion shrunk and the swelling went down the benefits were lost.

MBAnderson profile image
MBAnderson in reply to Juliegrace

I am sorry to hear that.

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