The MRIgFUS lesion shrinks. Who knew?

[MBAnderson]

That explains a lot.

" These lesions then shrink over time most likely due to scarring, and in humans, these lesions reach a plateau around 6 months after the RF91 and 3 months after the MRIgFUS interventions.65 92 93"

jnnp.bmj.com/content/89/7/7...

jnnp.bmj.com/content/89/7/727

researchgate.net/publicatio...

(You can find a blow up of this graph in the link.)

jnnp.bmj.com/content/jnnp/8...

[park_bear]

I wonder if the lesion shrinkage is due to the dead cells that got zapped being cleared out. Their function would not necessarily have been replaced.

[MBAnderson in reply to park_bear]

I am looking for the explanation

[rebtar]

Mark, could you explain for those of us who have some trouble understanding the clinical trial documents, what is important about this information?

[MBAnderson in reply to rebtar]

It might explain why if (or that) some symptoms might partially return after the FUS surgery.

[Juliegrace]

I knew this based on my experience. Or, at least. I am convinced this is what happened to me.

[Trixiedee in reply to Juliegrace]

Where and when did you have FUS?

[Juliegrace in reply to Trixiedee]

2016 in Baltimore as part of the research study for FUS pallidotomy. I’ve posted about it in the past.

[MBAnderson in reply to Juliegrace]

How satisfied are you with it?

[Juliegrace in reply to MBAnderson]

Not very as it did not last very long (4-6 months). My theory is that initially the lesion was bigger and there was swelling that gave me a better result, but as the lesion shrunk and the swelling went down the benefits were lost.

[MBAnderson in reply to Juliegrace]

I am sorry to hear that.