I asked on David Sinclair's Facebook page.

[Gcf51]

What do you think about: “Metformin Use Linked to Increased Dementia, Parkinson's Risk in Patients With Diabetes” medscape.com/viewarticle/87....

With NMN, niacin or NR I feel a slight tingling sensation inside my head which I take as my brain being energized, but metformin causes me to experience brain fog. I am not diabetic, but I feel I would be one of the ones that would develop Dementia and/or Parkinson's.

FYI - I was diagnosed with Parkinson's before I tried Metformin

I wonder if he will reply or make visible?????

[Hidden]

Good for you in asking!! Keep us posted! What about asking the doctor leading the huge TAME trial?

[Kerrybromas]

I have been diagnosed with Parkinson's disease since 2010, by the VA. I found that none of the current medications worked (side effects for me). I currently take pramipexole dihydrochloride three times daily. It isn’t working well neither. I still have some tremors. Was on carbidopa levodopa but only lasted 90 minutes then wore off. Down side of carbidopa is after reaching max dosage it will no longer give relief, nothing was working for me and to make matters worse there has been little if any progress in finding a reliable medical treatment for Parkinson's disease without spending thousands of $, finally this year I was introduced to Health Herbs Clinic and their effective Parkinson’s herbal protocol. This protocol relieved symptoms significantly, even better than the medications I was given.. No case of Parkinson’s, hallucination, weakness, muscle pain or tremors. I’m strong again and able to go about daily activities.

[Gcf51 in reply to Kerrybromas]

What herbs were recommended?

I never got a response from Sinclair. I also go to the VA.

[Kerrybromas in reply to Gcf51]

healthherbsclinic. c o m

[Gcf51 in reply to Kerrybromas]

I sent a private HU message.