Big pharma puts bets on alpha-synuclein i... - Cure Parkinson's

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Big pharma puts bets on alpha-synuclein in Parkinson’s – but will they pay off?

Farooqji profile image
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Several pharma companies think that targeting a rogue protein known as alpha-synuclein could be the key to halting or reversing neurodegeneration in Parkinson’s disease – but has the industry learned from a string of failures in Alzheimer’s? In the space of a few weeks, Novartis AG and Sanofi AS have signed major deals for molecules targeting misfolded alpha-synuclein, the rogue protein thought to be the root cause of Parkinson’s disease

bioworld.com/articles/51555...

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Farooqji
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kaypeeoh profile image
kaypeeoh

Is there any evidence that alpha-synuclein is the culprit rather than an innocent side effect?

jeffreyn profile image
jeffreyn in reply tokaypeeoh

There is clear evidence that alpha-synuclein plays a part.

The full extent of that part is not yet clear.

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