Does anxiety also make your symptoms horrible?
SSRI question. lexapro/celexa help my de... - Cure Parkinson's
SSRI question. lexapro/celexa help my depression and anxiety but worsen my symptoms. Will all SSRI or SNRI antidepressants do the same?
Written by
38yroldmale
To view profiles and participate in discussions please or .
Read more about...
16 Replies
•
Anxiety makes my symptoms worse.
This website below may help you at sometime. You can put in medications you are on and it will show you if there are any interactions.
"WellRed light helmet working good," you posted just recently. Isn't it working any longer?
Despe, the red light helmet is still working. I’m still up and very down at times. But 100% it helping me. My good days almost makes me feel like I don’t have PD. My bad days, maybe because of the contrast of better feeling good days are very low. Before the red light, I would have 2 days a week that were good, 5 bad. Now it’s 5 good and 2 bad. My depression and sleep is much improved, anxiety is still at times awful. I wrote this last post during a very down time.
I am very glad light therapy is working for you, and based on your experience and John Morris', we ordered it from Australia, but not here yet.
FYI, Lexapro is somewhat different than Celexa though both are older SSRIs.. They are not the same and presumably should not be taken together for obvious reasons... They both block Serotonin re-absorption which can be both good and bad since the key in PD is a "balance" between dopamine and serotonin.
SSRIs in general are heavy duty drugs to be handled with care. IOW, they can come with a load of negative side effects that outweigh any benefit for PD motor dysfunctions.
38 years old (let alone under 50) is rather unusual for a confirmed diagnosis from a PD experienced neurologist. Are you sure you have PD? What was you UPDRS score on part III? DaTSpect scan result?
Sharon
Sharon,
I have a very severe family history of Pd. No one near this early. Had some extreme stress from 13’ to 18’ when I was dx. I had a head/neck injury in 15’ when I can remember the symptoms starting. I have had positive datscan.
My first neurologist appointment was in Sept 2 2018 because my right hand was moving slowly. At that time I was on 20 mg of celexa. He said no Pd, but it was more of a nerve test. I didn’t believe him and increased to 40 mg of celexa. Had MRI, CAT scan and finally a datscan that confirmed Pd on Dec 26, 2018. During that. Short time I Developed stiffness, small tremor and gait issues. I think it might have been drug induced but turned to Pd. I thought for a while it was drug induced even with the positive datscan because I was took the 40mg of celexa the morning of the datscan which can skew the test. Also c/l did nothing. However I’ve been off srri it for a while with improvements but they seem to have stalled. I’ve been off them 6 months. I know it says sometimes it takes 2 years to recover from drug induced Parkinsons. I don’t want to pay for another datscan.
38,
Parkinson's can develop from overdosing long term on Celexa, an SSRI, which is a toxic drug (as are all SSRIs), which is well known by PD doctors who know these drugs create dopamine neuronal death leading to Parkinson's or exacerbating it. Severe depression can be the 1st manifestation of PD or one of many manifestations, but adding a SSRI isn't going to help you with your PD regardless of where you are in the progression.
I can't believe your neuro didn't know about this relationship unless he was totally inexperienced with PD, or did you even bother to tell him about your long term use of this SSRI and your significant history of depression? Should have been a huge red flag for any board certified neuro practicing in the US.
Sharon
Sharon,
Thanks for all of your help. My current neurologist had no idea SSRI could cause Drug Induced PD. Maybe time for a different one? I hate going anyway. I feel better off c/l and Rasgilline and they don’t seem to help. I don’t need PD meds anyway yet....
What about remeron? I need help with anxiety. I believe I am a low mentholater. Look at the attached link, my characteristics are almost 100% with low methylation. I suffer with low serotonin and dopamine anyway. Messing with my serotonin worsens my symptoms. Even rasgilline makes me depressed. Another protocol I am on Had me take folate, which was messing me up as well.
I’ve been following the advice from the attached link with really good results.
americanherbalistsguild.com...
38,
If you live in the US, make an appointment with your nearest "PD Center of Excellence". Plenty to choose from.
If you live in the UK, you have two such centers. Canada has several. Australia has one. EU has several in Italy.
Get a 2nd opinion. Don't try to wing it on your own.
"38 years old (let alone under 50) is rather unusual for a confirmed diagnosis from a PD experienced neurologist. Are you sure you have PD? What was you UPDRS score on part III? DaTSpect scan result?"
Sub 40 PD is relatively common. Well, not super rare. 1000 Australians a year are dx with PD before they are 40.
Having been through the process, I can assure you that both GPs and neurologists explore every conceivable alternative before they give a YOPD dx. I suspect that this brings down the false positive rate considerably.
sharoncrayn in reply to
Chris,
"Sub 40 PD is relatively common"...Wrong...way, way wrong. (I didn't say it was super rare. Don't take what I said out of context, please).
I have looked at the article on PD age cohorts for Australia by Deloitte for 2015 and 2019 and compared it with the huge NIH (Australia)2001 study.
Deloitte states that in Aus some 82% of PwP are over65.
#1 69,208 PWP in Aus in 2014
#2 986 in 25-44 age cohort
#3 .0142% = PWP in 25-44 age cohort (hardly common by any account)
versus....the NIH study (not the greatest study).
"In the cross-sectional study, 16/3509 participants were confirmed to have PD (0.46%), with age-specific prevalence rates of 0.48% in persons aged 60-69 years, 0.82% for ages 70-79 years and 0.56% in persons aged 80 years or older. No PD cases were identified among participants less than 60 years of age. When age standardized to the 2001 Australian population, the prevalence of PD was 362 per 100,000 (95%CI 183-541) among persons aged 50 years or older and 104 per 100,000 for the Australian population at all ages, assuming no prevalent cases in persons aged less than 50 years.
Sharon
in reply to sharoncrayn
Obviously it depends on your definitely of "relatively common" (and im not totally sold on the DTT stats because shakeitup are saying its 3 per day dx under 40) but regardless, it's sufficiently common that doubting someone's dx is probably not the best reaction. As i explained to you (and as 38 has subsequently confirmed was his experience), neurologists will consider every other possible thing before they dx YOPD. I suspect they are far more thorough with us than they are with the over 65. Consequently, by the time you have a YOPD dx, chances are pretty good you have PD.
sharoncrayn in reply to
Chris,
I said PD under 40 is "unusual". Please don't suggest I said anything else.
To my point, the incidence of 25-44 year olds in Australia diagnosed with PD in 2014-2015 = .0000406% of the total population of 23,800,000. I think you understand what that means.
Shakeitup got their info from the Deloitte report who got it from the Australian Dept. of Health.
Sharon
in reply to sharoncrayn
Such pointless pedantry on your part. Boy am I glad I am not a member of one your 'support groups'. Perhaps the strategy there is to make PD comparatively manageable. "I thought PD was hard work. Then I attended the support group."
sharoncrayn in reply to
Chris,
My support groups are closed to new memberships until Jan1 when we open for new enrollment.
Sorry.
in reply to sharoncrayn
I suspect that it's relatively straightforward to amend the rules of a support group that exists exclusively in your head so I urge you to reconsider.
