Has anyone heard of any trials involving brain stimulation? it's happening with athletes to improve performance.

[Getz]

medgadget.com/2019/07/unloc...

[JohnPepper]

Yes! To the best of my knowledge studies have been done on WALKING. I don't keep records of studies but I am sure somebody does.

My experience has been that Fast Walking stimulates the production of GDNF, which we all know repairs or replaces damaged Glial cells, which is the cause of our brains being short of dopamine.

[Getz in reply to JohnPepper]

Yes John. I agree totally with your fast walking for an hour 3 days a week but this link has wonderful potential. It seems that there's no downside but there is absolutely no claim that it may have medical benefits (which would immediately shut it down by your FDA). Just wondering if anyone has trialed it and had an improvement.

[JohnPepper in reply to Getz]

I don't know quite what you are asking me here. I am not aware that the FDA has a right to interject in what exercise in which anybody takes part that can possibly alleviate the use of a medication currently being taken.

Am I off the mark?

[Getz in reply to JohnPepper]

Obviously the FDA cannot interfere with exercise or gym workouts but this is a scalp stimulation exercise who make no claim for medicinal benefits. The thing is it hasn't been tested for such but may have great benefits. I am just wondering if anyone has tried it and had benefits. If it improves endurance performance, music and memory performance, the chances are that it will improve PD.

[JohnPepper in reply to Getz]

A very big chance but who will pay the costs of a study? It does not put money into anybody'd pockets it only makes the lives of Pd patients a lot more enjoyable. But who cares about that?

[Getz in reply to JohnPepper]

John, just off the top. I go like the clackers fast walking for an hour to get 6kms. How in blazes do you get to 7 kms and you're 10 years older than me?

[JohnPepper in reply to Getz]

See my reply to Getz'

[Getz in reply to JohnPepper]

John, off the cuff I'd like to know how you get 7km/hr and I can only get 6 in an hours fast walking. I'd also like to know if its ok to walk like the clackers for 30 mins then stop for a coffee then walk back again. I read of a formula for my age being heat rate of 122 beats/min so I'm wondering if in our wet season you could do treadmill, cycle, rowing machine. Is it the heart rate or is it the walking?

[JohnPepper in reply to Getz]

It took me four months, starting walking for only 20 minutes, which I had been doing in the gym, every day for over 20 years, every second day for two weeks. After every second week I was allowed to increase the time by 5 minutes, When I got to one hour I had to stay at that time. Then all I did was walk as fast as I could and after two years I got up to 9 Ks an hour, at the age of 64.

If you are not walking at maximum speed, nothing happens. If you walk every day, you don;;t allow your muscles to recover and you don't improve.

Try following these rules, EXACTLY and tell me how it goes.

How do you know if you are walking as fast as you can? If you can still talk to somebody then you are not walking as fast as you can. If you can't talk at all, you are walking too fast. You should only be able to say two or three words between breaths.

[sharoncrayn]

Many, many (probably more than 70+ references) DBS studies and clinical trials have been completed or started over the last 35-40 years. Some are intrusive (surgically implanting an electrode or attaching it in some manner); some are not. DBS is an old, old study discipline for PD . Started way back in the 1980s.

You might want to reference the NEJM Sept 2001 issue. Good CT.

If you are truly interested, Call the National Institute of Neurological Disorders and Stroke and ask for their list of current work in progress or completed recently.

My overview of the DBS history is that the "intrusive" DBS studies and CTs were more successful than the "non-intrusive". However, they also had negative connotations as we would suspect.

S