NIH awards Cleveland Clinic $3 million gr... - Cure Parkinson's

Cure Parkinson's

26,583 members27,899 posts

NIH awards Cleveland Clinic $3 million grant to determine effects of exercise in Parkinson's

Farooqji profile image
3 Replies

The new study aims to determine if long-term, high-intensity aerobic exercise can slow the advancement of Parkinson's disease, a progressive neurological disease.

eurekalert.org/pub_releases...

Written by
Farooqji profile image
Farooqji
To view profiles and participate in discussions please or .
3 Replies
jimcaster profile image
jimcaster

For anyone capable of doing it, high intensity exercise appears to be the most likely way to slow or stop the progression of Parkinson's disease.

jeffreyn profile image
jeffreyn

Some of you will be familiar with Jay Albert's CYCLE trial. The new trial is, in effect, CYCLE Mark 2:

"Cleveland Clinic and University of Utah will recruit 250 Parkinson’s patients who will be randomized to a high-intensity home exercise or usual and customary care (UCC) group. [The high-intensity home exercise group will follow the protocol from the CYCLE trial, and will] utilize indoor cycling bikes from fitness technology company Peloton. Participants will be instructed to exercise 3x/week for 12 months; the UCC group will be instructed to engage in their normal activities."

Rlp1 profile image
Rlp1

I ride a road bike 100 miles a week. I have had stable numbers (UPDRS) since diagnosis in 2014. I think it makes a difference.

Not what you're looking for?

You may also like...

Levodopa: Molecular Effects of L-dopa Therapy in Parkinson's Disease.

Molecular Effects of L-dopa Therapy in Parkinson's Disease. 2014....
aspergerian profile image

With exercise, John Cullen was able to slow and even reverse the progression of his Parkinson's symptoms

PARKINSON'S DISEASE HAD caused 61-year-old John Cullen to slouch and drag his foot while walking....
Farooqji profile image

Integrating Network Pharmacology, Transcriptomics to Reveal Neuroprotective of Curcumin Activate PI3K / AKT Pathway in Parkinson's Disease

A mouse study, and just an abstract, but it is pro-curcumin and so am I so I am sharing it:...
Bolt_Upright profile image

Sodium Butyrate: Neuroprotective effects of short-chain fatty acids in MPTP induced mice model of Parkinson's disease 2021

https://pubmed.ncbi.nlm.nih.gov/33905875/ Gut microbial metabolites, SCFAs, were related with the...
Bolt_Upright profile image

Long‐Term Safety and Clinical Effects of Nilotinib in Parkinson's Disease (Nov 20, 2020)

Georgetown University asked me to share the most recent paper on Nilotinib with you all....
pmmargo profile image