Novel device opens new doors for Parkinson's disease diagnostics

[Farooqji]

Currently, there are no disease-modifying therapies for the treatment of Parkinson's disease; however, one potential strategy for treatment is to prevent α-synuclein aggregation. As a first step, researchers at Osaka University have developed a device that can assess the degree of α-synuclein aggregation in the brain.

m.medicalxpress.com/news/20...

[Xenos]

I like it...but I am unable to even begin to understand how this works. Ultrasonification !?...

[Farooqji in reply to Xenos]

it simply accurately detects α-synuclein aggregation in cerebrospinal fluid (by detecting seeding activity of α-synuclein aggregates in cerebrospinal fluid) using ultrasonification technique (sound energy at high frequencies )

[Farooqji in reply to Xenos]

Step by step details of the process are mentioned in the below link

nature.com/articles/s41598-...

[Xenos in reply to Farooqji]

Thank you iqbaliqbal. This is much clearer, even though I still have to figure out how molecules as small as alpha-synucleins can change anything on sound waves.

I will read your document more thoroughly.

[condor39]

I don’t understand “Currently, there are no disease-modifying therapies for the treatment of Parkinson's disease”??????

Maybe it is playing with words, but along with many thousands of patients, my PD is very modified with Prolopa Madopar)