I know it's in Italian , but I think it's worth sharing. It talks about Palmitoiletanolamide , a molecole that supposedly works on the inflammatory state of the brain and from what they say with very good results for parkinsons ( they say thrilling). I stress that it is a public research of our national health service, not from someone who seeks fame or money. has anyone ever heard of it?
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Lucal
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Hi Lucal, on April 9th some newspapers, even national ones, talked about this little (30 pwp) study of 2016 conceived by Dr. Stefania Brotini, a neurologsit at the Empoli Hospital. Um-Pea, ultramicronized Palmitoylethanolamide, it's a molecule known for its ability to promote the resolution of neuroinflammation, appears to slow PD progression when used an adjunctive therapy. The molecule was discovered by Rita Levi Montalcini, our Nobel prize winner. It's a counter product, it's called Normast. With the doctor I made an appointment for nex May.
Empoli, 10 April 2019 - Combating Parkinson's disease. Curbing the symptoms and containing them results in the daily lives of patients, so as to guarantee the latter better living conditions. This is the objective of the study carried out with dedication and very interesting results by Dr. Stefania Brotini, a specialist in neurology and an expert in degenerative diseases and sleep disorders, thanks to the staff working at the hospital in Empoli. A new challenge against a disease that "represents the most common neurodegeneration of movement disorders", as explained by doctor Brotini, born in 1964, graduated in medicine and surgery at 'University of Pisa and specialized in neurology with the highest grades and honors. A path of constant research, his, made up of workshops, seminars, congresses and studies that led her to this new path of care that means hope. Hope enclosed in the innovative anti-neuroinflammation therapy that manages to counteract involuntary muscle movements and reduce motor blockage. But not only. The course of care also brings other benefits that relate to sleep quality, paresthesia and mood, returning a good quality of life. All this emerges from the ‘made in Empoli’ study published in the international scientific journal Cns & neurological disorders drug targets. The starting point is represented by the fact that "numerous scientific data underline the role of neuroinflammatory phenomena in the uncontrolled progression of pathologies such as Parkinson", explains the expert who, during her research, highlighted the importance of a molecule , ultramicronized palmitoylethanolamide (Pea-um) able to counteract the onset of neuroinflammatory phenomena. Hence the idea of evaluating a particular administration of the 'substance' in a group of parkinsonian patients.
"The results were exciting," emphasizes Brotini, then explained that "in addition to classical therapy, Pea-um can act as an effective adjunct to reduce involuntary movements or the duration of motor block. It therefore reduces the side effects of the disease and traditional therapy and delays the course of the disease even at an advanced stage ". Basically, the addition "has shown a significant improvement in motor symptoms, but also in many non-motor symptoms". A novelty that can help patients and those around them.
Explaining a medical term in Lucal's Italian article, as translated above by dreilly942:
"The course of care also brings other benefits that relate to sleep quality, paresthesia and mood, returning a good quality of life." So what is paresthesia?
*par·es·the·si·a /ˌperəsˈTHēZH(ē)ə/
noun: paraesthesia; plural noun: paraesthesiae, or paraesthesias;
an abnormal sensation, typically tingling or pricking (“pins and needles”), caused chiefly by pressure on or damage to peripheral nerves.
Ex: "patients complain of painful paresthesiae in the hands"
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