Fasting

Four grams a day, thiamin hcl.

Regarding tremor and mealtime, I am trying to determine when to eat and when to dose. After my five a.m. dose and not having anything on my stomach all night, no tremor. After breakfast tremor returned.

[jujulini]

do you think your dose could be too high, since the tremor returns after you take the dose?

[Hidden in reply to jujulini]

Three hours no tremor. Then breakfast, then tremor

[Syncletica in reply to Hidden]

Roy, I, too, have a similar experience. Do you take the Thiamine and PD meds at the same time--on an empty stomach? Have you experimented with separating the Thiamine from the PD meds?

[Hidden in reply to Syncletica]

Yes and no

[Kia17]

Roy

If your tremors get worse after food then have your insulin resistance checked.

[Hidden in reply to Kia17]

"The following are all risk factors for insulin resistance, prediabetes, and diabetes, and some can be modified by lifestyle changes or medical help:

Overweight and obesity (primarily abdominal obesity)

Sedentary lifestyle - not engaging in physical activity regularly

Smoking

Sleep issues"

I do not smoke and not overweight. Hmmm!

[Kia17 in reply to Hidden]

Roy

That doesn’t include all the signs. You might have brain insulin resistance.The insulin resistance is very complex issue. I would have checked my blood sugar, HbA1C, and tried low carb diet for sometimes.

[JAS9 in reply to Hidden]

Diabetes is caused by fat inside your cells, so you can be thin and still have it. Here's a short video explaining in very straight-forward way what's going on with diabetes. Some funny stories too. youtu.be/ktQzM2IA-qU(Not working as expected?)

[2bats in reply to JAS9]

There’s a great documentary called The Magic Pill, which is fascinating - and much more convincing than Neil Barnard. It’s on Netflix

[aspergerian13 in reply to Kia17]

Kia17 point is important.

[KERRINGTON]

A simplistic thought, but for what it's worth, no tremor after all night, and 5 AM till breakfast, so your stomach has been empty from approximately 11 PM the night before till breakfast. Your body/stomach/brain did not have to share the 5 AM dose, 2 gms with food digestion etc. It had the 2gm dose all to itself...Once you ate breakfast and took your next 2gms, the thiamin dose gets mixed up in the digestion/absorption process and has competition. So maybe when taken near a meal/food we need to increase that dose. For instance, many meds potency diminish when taken with food . Maybe that's why the tremors returned after breakfast ??

[Hidden in reply to KERRINGTON]

Tremors all night. Stop after 5am meds. Start again after 8am breakfast

[jujulini in reply to Hidden]

it could still be the food interfering with the meds. im assuming you dont take any meds at night, and then the meds take care of the tremors at 5 am, but then you eat, and the meds are competing with the food, and then the tremors return???

[KERRINGTON]

Oh, didn't realize that, but there could still be a possibility that food diminishes thiamine's action.

[LAJ12345]

What do you eat for breakfast? And what other supplements do you take with breakfast?

[wriga]

Hello Roy.

I think you may have made a significant observation. I have observed that my symptoms get worse after a large meal. I have now gone onto a low carb diet (soft keto) alongside B1 3.5 g, 2g before breakfast, after viewing the video W Curtis recently posted by Kia. So far I've lost weight but too soon to draw a clear conclusion.

My question is "What constitutes your breakfast?". Is it high or low carb, and does high or low carb (or other variants - coffee, tea, milk etc. ) make a difference to your observation? I'll be making the same tests on this side of the pond.

[Kia17 in reply to wriga]

Wriga

Even a small amount of carbs have a huge negative impact on symptoms.

I would say Thiamine and Keto or even semi-keto diet can change the PD equation alot.

[felixned in reply to Kia17]

Interesting. I react poorly to any animal protein and HCs are fine. Overall calorie reduction seems to be beneficial.

[Maxkas]

My tremors disappeared after I stopped eating gluten

Anf I do not eat anything 1hr before & 1hr after PD meds

Good luck 🌸

[Hidden]

Today:

5am, took meds and then back to sleepy with tremors.

7am, awoke, no tremor, watching Senators vote Judge Kavanaugh to SCOTUS.

[SufferingSocks in reply to Hidden]

What do you mean by Senators voting Judge Kavanaugh to SCOTUS? What does that mean? We've been watching the news about his troubles and haven't heard results yet. Suffering Socks

[Hidden in reply to SufferingSocks]

I eat rice.

[Cons10s]

The thiamine is beginning to positively reduce your tremor time daily. That’s similar to what happened to my tremor on B1.

I had an intermittent tremor I describe as a 4/5 on a scale of 1-10. Ten being the worst. Now it’s a 1/2, but mostly a one or none due to B1.

My tremor began to disappear at different points during the day and I too thought it was food at first.

B1 since April, tremor reduction occurred during the last 2-3 months until now where it’s almost gone.

Try not to over think it. That helps a lot. I went to Europe for 18 days and because I was distracted my tremor further disappeared. This has remained constant since my return.

Just say “ the B1 is working”. And get busy on something else. And as Dr. Constantini says “you’ll be fine forever”.

[Gioc in reply to Cons10s]

Cons10s, I agree.

That's a good idea. The b1 works even if we don't think about it.

When I have a few stressful days and the symptoms seem to get a little worse, I ignore it and go straight for my way, so I'm sure I'll soon get back in good shape as before, whether I worry or not.

Gio

[James4K]

Dear Roy, I too have a similar experience. In the mornings my tremors are very diminished, but after breakfast they become very pronounced. I have tried several ways of taking B1; before breakfast, during breakfast, and after breakfast but still the same results. My tremors seem to only improve in the evening, starting around 4 PM. I definitely believe that my B1 regiment is having a positive effect, just wish it would start working early in the day. I take 4 g a day. Looking forward to other replies!

[Abdiqani]

Fasting has many health benefits not only PD and still further conducting researches to know more about its positive impact on Conditions .

[Hidden]

Yesterday I moved my morning and afternoon dose schedule from the 5 to the 8 hour. Today at two in the morning my tremor is level 0 to 1 on a scale of zero to nine.