May be helpful.
The spectrum of "off" in Parkinson's disease: What have we learned over 40 years?
Review article.
Chou KL, et al. Parkinsonism Relat Disord. 2018.
ncbi.nlm.nih.gov/m/pubmed/2...
Abstract.
The terms "on" and "off" were used by Marsden and his contemporaries over 40 years ago to describe times when Parkinson's disease patients experienced good motor function ("on") and immobility ("off"). Yet there remains no published consensus definition of "off", leading clinicians and patients to develop individualized impressions of "off" determinations. In this paper, we first discuss the evolution of the terminology and understanding of "off" states since Marsden's time, which now include non-motor as well as motor symptoms. We then review pathophysiology and risk factors for the development of "off" states as well as tools to detect the "off" state, before proposing a practical definition of "off" for consideration. A common, practical definition of the "off" state could improve clinical recognition of "off" symptoms and lead to significant benefit for patients.
PMID 29456046 [ - in process].
I've been reading about the benefits of Forced Exercise and exercise rate on bicycles and its effect on PD symptoms. 
Gut microbes may be the root cause for PD
Dyskinesia: Lessons from Africa
Was this patient's long history of meditation a factor in the remission of his PD? 
