Some Background information - Dr Contantini MD

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Antonio Costantini MD, Maria Immacolata Pala, Laura Compagnoni, Marco Colangeli.

Papers Published

PMC [2016 MarPMC4828997]

An open-label pilot study with high-dose thiamine in Parkinson's disease

BMJ [BMJ Case Rep. 2013; 2013: bcr2013009289.

Published online 2013 Aug 28. ] Cited by 17 Related Articles

10 Apr 2018 - Cited this publication. Antonio Costantini ... 15+ million members; 100+ million publications; 700k+ research projects.

Latest Report in BMJ - 2018 :

BMJ Case Reports 2018; doi:10.1136/bcr-2017-223945

Findings that shed new light on the possible pathogenesis of a disease or an adverse effect

CASE REPORT

High-dose thiamine and essential tremor

Antonio Costantini

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Author Affiliations

Department of Neurology, Villa Immacolata, Viterbo, Italy

Correspondence to Dr Antonio Costantini, [e-mail]

Accepted 18 March 2018

Published 30 March 2018

Summary

Essential tremor is a common neurological disease. The medical treatment of this affection currently involves the use of propranolol, primidone and other drugs. These drugs, however, are often not effective in reducing tremor and cause side effects in a large share of the patients treated. The treatment with intramuscular high-dose thiamine has led to a rapid, remarkable and persistent improvement of the symptoms in two patients with essential tremor. This result suggests the possibility that high doses of intramuscular thiamine may be an affordable alternative, highly effective and long-lasting medical treatment that has shown no relevant side effect.

Further reading concerning the earlier background can be seen by following this link

ultimaedizione.eu/2015/04/2...