Who makes your medicine. Does it make a difference.

[Bailey_Texas]

I take carbidopa levodopa 25/100 and it works great. Last week my carbidopa levodopa was not working the same and some times not a all. I went one day with no relieve at all. I just happened to notice the maker. It was one that i did not know. There are several different makers. I had some left over carbidopa levodopa by my usual maker and used it. That day i was back good again. Anyone else had this happen.

[laglag]

Bailey

I had the same thing happen to me a couple of years ago. All of a sudden they changed manufacturers of my Parcopa, which is a dissolving on your tongue type of sinemet. They changed it from Mylan to Sun. Don't remember the exact timeframes, but it was within a few days I noticed my symptoms were worse & it wasn't lasting as long. I also had some left over from Mylan so I switched back & started feeling better again. I called the pharmacy (Express Scripts) and they said they would have to start charging me a huge amount to change back. They also said all the "active" ingredients in generics are supposed to be the same, but I knew there was something different because the difference in my symptoms were like night & day. I ended up calling the mfg. and talking to several people and found out that Mylan was the generic. So I talked to Express Scripts again & they checked on it & realized it was the generic so they switched it back & did not need to charge me extra. So stick to your guns and talk them into changing it back. Different mfgs do make a difference. Good luck!

[hopedope in reply to laglag]

Express Scripts is our pharmacy too. My c/l used to come from Teva but the last two bottles have been from Mayne. I have noticed that I have some foot pain now and some back shoulder blade pain lately--I think the pains might be related to my Tai Chi classes and to recent exercising during a 4 week balance class at the Y. Thank you for the reminder that we can call the pharmacy.

[BUZZ1397]

Dang right! It's "criminal" the way some generic producers have very low potency. There ought to be a way to get some revenge on the s.o.b.s. My advice is try taking it back to the pharmacy and requesting your prescription be not filled by that pharmaceutical company. i've done that for my spouse with one of her MS drugs and luckily they were cooperative about it.

[Bazillion]

The same thing happened to me with Mirapexin . Pharmacist says shouldn't make a difference but I know how much different I felt.