Lypospheric gsh

[Nimvas5962]

I want to know if any of you has used lypospheric gsh and what was their response it terms of reductions in dopa dose.

Thanks

[silvestrov]

Here is a thread about a HU participant who used Nasal glutathione:

healthunlocked.com/parkinso...

[Nimvas5962 in reply to silvestrov]

Dear S,

It is indeed heartening to see that a person like u is always there for me. I am not doing too well . My left leg goes into spasms of pain ... the adductor longus tendon .l am undergoing intensive physio which is very painful. I have fought with my neuro guy who feels alternative therapy with supplements is crap. Anyway I got in

touch with top mov disorder specialist dr Laurie mischley who has recommended lypospheric gsh by liv on labs. It takes 3 months to arrive by Amazon so my mother is asking her friend to get it by Dec 1

I also am considering lypospheric vit c 10000mg .

I have imported whey isolate as it acts as a liver detox glutathione boost

Also I have started on a nuts and seed diet.

I am full into alternate therapy , it's my body its I whom is suffering I care a damn what my neuro guy says

Wish me luck

Vn

[silvestrov in reply to Nimvas5962]

My pleasure. Be careful with whey powder because it is a good source of branch chain amino acids and BCCA interfere with the absorption of levodopa. Certainly they will help to raise glutathione levels but hopefully at the expense of levodopa therapy.

BCAAS AND WHEY

Despite the numerous positive benefits to BCAA supplementation, there are many skeptics who suggest that BCAAs are overpriced and that, to get more BCAAs, one should just consume more whey protein. While whey is rich in BCAAs, this isn't the most effective strategy.

bodybuilding.com/fun/bcaas-...

Branched-Chain Amino Acids

Amino acids referred to as branched-chain, or BCAA, directly interfere with levodopa absorption. Leucine, isoleucine and valine are the three branched-chain amino acids that inhibit levodopa absorption more than other amino acids obtained from protein. Foods high in BCAAs include red meat, dairy, chicken, fish, poultry and eggs. Protein powders and whey supplements, a high-quality source of protein produced during the making of cheese, are also rich-sources of BCAAs.

livestrong.com/article/4358...

So perhaps you should consume whey protein in the evening - long after your last dose of levodopa. And if you have to take an evening dose I expect you to have a severe 'off' time in the morning.

NAC, n-acetyl l cysteine has been shown to be good for PD and it raises glutatione levels:

news-medical.net/news/20160...

antioxidants-for-health-and...

The above article also mentions alpha lipoic acid, which is good for PD:

ncbi.nlm.nih.gov/pubmed/204...

There are multiple forms of alpha lipoic acid (ALA) and the best one is R-ALA. Many brands use a combination of R and S (synthesized) ALA and S is not as good as R. Acetyl l Carnitine also raises glutathione levels and is mentioned in the above article.

blog.luckyvitamin.com/suppl...

[Nimvas5962]

I intend to take whey at night. My last dose of dopa is at 5 pm.

My major protien is 3 scrambled eggs at 7pm.

Theanine is working like a charm.

What about lipossphere vitC 1000mg

[silvestrov in reply to Nimvas5962]

lipossphere vitC... With liposhere or sometimes it is called liposomal gutathione, it is much better absorbed than normal vitamin C so take it slow, say 1/2 dose, to ease your body into this supplement. 1,000 mg should not cause diarrhea like large doses of vitamin C can do. When I was on my adrenal therapy I took over 23,000 % of the daily dose of vitamin C, including 3 times the daily dose of liposomal glutathione, and the doctor continuously asked, do you have diarrhea? I never had it once. Once you get used to this amount you can up your dose if you like and remember that vitamin C can be taken up to bowel tolerance (diarrhea). Linus Pauling took 12,000 mg/day of ascorbic acid till he died at the age of 93. AIDS patients have taken between 50,000 and 200,000 mg/day of ascorbic acid with no side effects! Generally speaking, the greater your illness the greater the demands of vitamin C and 'bowel tolerance' is much higher than a normal healthy person. To this day I take 5,000 mg/d of time release ascorbic acid.

Have a good day and I am off to bed. I am still nursing a cold and want to sleep well.

[park_bear]

I have used several forms of glutathione so I am in a position to compare relative ease of use.

1. Lypospheric GSH is a very sulfurous mouthful to get down. If my health depended on it I could manage it but not exactly my favorite.

2. The Glutagenesis version of glutathione requires refrigeration during transport, is quite expensive, and has a number of added ingredients: NAC, mannitol , inositol, and rosemary extract. I find it a bit acrid probably due to the rosemary extract. I question whether these added ingredients make any difference. NAC and mannitol are readily absorbed via ingestion and these are needed in much larger quantities that one would get from inhalation.

3. L-Glutathione plus from Theranaturals. Reasonable in cost and a pleasant aroma when inhaled from an nebulizer. Definitely my favorite. Comes as a dry powder in capsules. To nebulize open a capsule and shake the powder into a couple of mL sterile saline.

Also choice of nebulizer matters. I am currently using an ultrasonic version which takes forever - an hour or so - to nebulize a couple of mL of fluid. I have something better in the way which is said to do the same in minutes instead.

[Nimvas5962 in reply to park_bear]

If u disregard the taste does it make a difference to ur PD. Since the first of the month my dopa dose has increased three fold and intense parasthesias afflict my left leg. I am frankly tired and dr Laurie is the foremost authority for glutathione and she vouches for it. I'm praying I will get better by New Years and the dopa dose will go down

[park_bear in reply to Nimvas5962]

I have not done any of the glutathione treatments long enough to get a result. I do take NAC religiously and it may have stabilized my condition. It has been shown in a controlled trial to improve PD. Here is the study: journals.plos.org/plosone/a...