Some of you might have seen my other posts - if not then a quick recap:
December my father becomes very ill, large tense ascites, Hepatic Encapathology and pre-existing cirrhosis. He quit drinking about 2 years ago. He was admitted to hospital (in December) and was suffering from AKI (Acute Kidney Injury/Kidney Failure). They managed to patch him up and he has been going for regular drains ever since.
The time between the drains has been getting ever shorter - when I say drain, they are large - between 14 and 20L.
I have noticed over the past few weeks a change in skin tone which I understand is not abnormal, that will be his billirubin levels rising.
So, anyway - back to my reason for posting!
He was admitted to hospital on Tuesday for some investigation as the HE was no longer being managed by the refraxamine (spelling?), suspected SBP and there were signs of a GI bleed (blood in underwear etc), whilst he was in the hospital he was to have his drain.
14 days ago (previous drain) he creatinine had dropped significantly, to below 70 which was an excellent result, INR was at 1.2 and stable.
Bloods were performed on Tuesday and his Creatinine has increased to over 200, he is back at AKI. The docs will not give us the full picture with regards blood results or GFR unfortunately so at this moment in time we do not know where we stand.
When speaking with the doctors yesterday, they advised that the results of the ascitic fluid draw appear to be negative for SBP, however they are still waiting for the blood cultures to confirm this catagorically. They have said that this can happen when someone is suffering from HRS.
Now, obviously when he was in AKI previously this was one of our major worries and looking at how quickly things have escalated I have come to the assumption that this is stage one, the bad one. I have based this on the following:
Little/No improvement in Creatinine levels after 1.5L of IV Saline
Little/No improvement in Creatinine levels after IV Glypressin (Terlipressin)
The extremely fast increase in the Creatinine levels
The "hand flap" test which the doctor performed
The fact that the HE is no longer being controlled (to the same extent) by the refraxamine.
He is 68 - the doctors have said that they'll try and get him on the emergency transplant list, any ideas how likely this is?
With all this in mind, does anyone have any idea or experience of what we can expect?
Thanks in advance.