My mom's report for HER2 is 2+(equvivo... - Breast Cancer India

Breast Cancer India

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My mom's report for HER2 is 2+(equvivocal) by FISH method. so what does it mean? is HERCEPTIN advisable?

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jigarbahety
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rgci13 profile image
rgci13

Dr. Sumeet is the best advisor. We are in his forum under his guidelines. Happy New Year!

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sumeet_shahAdministrator

Jigar,

2+ is always on IHC (ImmunoHistochemistry) and not in FISH. When someone has 2+ on IHC, we advise FISH to be done, to confirm whether the HER2 gene is 'amplified' or 'not amplified'. I guess you have a bit confusion there. WIll you please let me know, whether the FISH result is 'amplified' or 'not amplified'. If amplified, Herceptin will be beneficial.

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jigarbahety

What are the best medicines for chemo ?

Doctor is saying for TAC method.

And will give 6 cycles after every 3 weeks

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sumeet_shahAdministrator in reply to jigarbahety

yeah, that's a standard chemo. Go ahead and follow your oncologist.