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A new study suggests coronavirus antibodies fade over time – but how concerned should we be?

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Newly released research suggests that levels of antibodies against the coronavirus have declined across the UK population since testing began. Having randomly sampled 365,000 people across the country, the React2 study – which is yet to be peer reviewed – estimates that 6% of the UK population had antibodies against the virus in late June, but that this had fallen to 4.4% by September.

If antibodies fade over time, how worried should we be? Does this mean we cannot be immune to COVID-19? To answer this question, we need first to consider what antibodies are and what they can tell us about immunity.

When we are infected, our immune system quickly responds to try and contain the threat and minimise the damage infection causes. This initial stage of immune reactivity is covered by immune cells known as innate cells that are resident in our tissues, which use a range of fairly generic strategies to both recognise and kill off the infection. But to truly deal with an infectious challenge, we need another part of our immune system – our lymphocytes.

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sassy59 profile image
sassy59

Very interesting indeed. There’s always hope.

Thank you 2greys. Xxx

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2greys in reply to sassy59

Very much so, I have read an awful lot on the matter of B-cells and T-cells and see this as the greatest real hope that we have. Antibodies may well fade in time, that is not an issue though. B-cells can make more as and when we need them on the instruction of the T-cells plus some of the T-cells are killer T-cells which will kill infected cells thus stopping the virus from replicating. The dead cells are replaced with new ones so there is no actual cell loss.

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