A single-center observational study of more than 1,000 oncological examinations has demonstrated that positron emission tomography/magnetic resonance imaging (PET/MRI) facilitates cancer staging as well as PET/computed tomography (PET/CT) and improves lesion detectability in select cancers, potentially helping to promote fast, efficient local and whole-body staging in one step. The study, published in The Journal of Nuclear Medicine, also shows that PET/MRI significantly reduces overall radiation exposure when compared to PET/CT—of particular benefit to pediatric and adolescent patients.
While PET/CT is known as the diagnostic cornerstone in various oncologic imaging guidelines due to its sensitivity and high-resolution morphologic imaging, PET/MRI has higher soft-tissue contrast and lower radiation exposure. However, clinical data for PET/MRI are scarce due to the lack of clinical studies with relevant sample sizes.
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Journal of Nuclear Medicine: