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Perspective: T cell responses to COVID-19 are a crucial target for research.

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While early research on the adaptive immune response to COVID-19 primarily looked at antibodies, more information is now emerging on how T cells react to the SARS-CoV-2 virus - addressing a crucial knowledge gap, say Daniel Altmann and Rosemary Boyton in a new Perspective. While antibody responses are generally much easier to study, T cells are known to play a more important role in protecting the body against viral infections. In the context of COVID-19, "antibody responses appear short-lived and T cell memory is potentially more durable," Altmann and Boyton say, leading them to argue that "it's time to admit that we really need the T cell data too." Seeking to assess the current state of knowledge on how T cells respond to the SARS-CoV-2 virus, the authors selected 9 studies - some published in peer-reviewed journals, while others are still under review and available as preprints - and summarized key takeaways and emerging points of consensus. "To fully understand population level immunity, screening for both antibody and T cell immunity using standardized testing methods would be beneficial," Altmann and Boyton conclude, noting that standardized tests to measure T cell immunity to SARS-CoV-2 could be designed using methods in common with established tests for T cell immunity to Mycobacterium tuberculosis.

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Boudica1

Hi 2greys, I have just been reading about this as well. I have plenty of T-cells if anyone wants some, but mine have a thing about my skin confirmed by a biopsy. They're still trying to get to the root cause and so far said Urticarial Vasculitis and Jessners Lymphocytic infiltration, Sjogren's Syndrome or some type of lupus.

Sorry if it seems like a flippant response, not intended at all but the amount of T-cells running riot are a blasted nightmare at times.

Maybe some of the 3 monthly blood tests they keep doing is going to the research bods either that or there is a café for vampires somewhere in the hospital.

X

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