I was only diagnosed with PAF a couple of months ago and at present, my episodes are of very short duration and fairly infrequent. I was initially prescribed Flecainide but the side effects were awful so the cardiologist changed them to Bisoprol 2.5. I can hardly drag myself to work every day and feel very depressed for no apparent reason. I feel a bit embarrassed to go back and say that this doesn't suit me either. Has anyone found that the side effects do settle after a while? My blood pressure has reduced which is a positive!