active surveillance?

[pd63]

Recently diagnosed;

Saturation transpireneal biopsy,gleason 3+4, 12 of 24 cores including targeted srea shown on mriscan (small area on one side),8 cores grade 3 4 grade 4, psa 4.2 dre normal and no symptoms.

If possible want to avoid treatment due to serious side effects,urologist mentioned possible active surveillance when he looked at scan and before biopsy, hospital appt next week to discuss with consultant.

Fit 65 year old wanna carry on for 2/3 years before biting the bullet.

comments please

[Tall_Allen]

It sounds like a lot of pattern 4, although I can't really tell from your description.

[pd63 in reply to Tall_Allen]

8 cores grade3, 4 cores grade 4 out of a total of 24 cores, been given T2 grade localised cancer.

I really don't want treatment for maybe a couple of years, prostatecancer website states possible surveillance, value near life quality rather than adverse side

[Tall_Allen in reply to pd63]

Sorry, what you are writing is meaningless.Cores are not "Grade 3" or "Grade 4" - they are either expressed as a Gleason sum (e.g., 3+3 or 4+5) or as an ISUP Grade Group, but I'm sure you don't mean ISUP Grade Group 3 or 4, which would disqualify you from AS. If you obtain your biopsy report, it will tell you what % of each core had cancer and what was its Gleason score. It may also tell you the % of each minority pattern.

[pd63]

glesson 3+4

[GP24]

The guidelines do not recommend AS for Gleason 3+4. I would recommend LDR brachytherapy as an alternative for surgery or standard radiation.

[pd63 in reply to GP24]

consultant has already mentioned AS as a possibility, appt on Monday to

[Alturia]

It's hard to know whether you are a suitable candidate for AS with the information you have shared. You say that you are staged at "T2 grade localized cancer." But are you ct2a, ct2b, or ct2c? I ask because it makes a big difference. According to the NCCN guidelines, you can be ct2 favorable and AS is one of the SOC options. Or you can be ct2 unfavorable in which case AS is not an option. In my view you need to look at the NCCN guides to try to understand the recommendations for your specific stage and then listen to what the consultant recommends. Here's a link to NCCN, you can create an account and then read or download the most recent guidelines.

nccn.org/

Here's a link to the most recent guidelines. See page PROS-2 to get started

nccn.org/professionals/phys...

[pd63]

Acording to the info in the prostatrcancer uk book, I'm potentially AS candidate, they don't use the T abc's anymore not saying I'm going down that route just really reluctant to have hormone therapy with it's harsh side effects radiotherapy or similar yes, surgery big NO, don't want pads on forever, will know more on Monday, I do value QOL near time while I can

[Hidden]

Looks like you've caught it early. Don't drop the ball by refusing treatment at this stage. Radical prostatectomy is the most invasive treatment and one most likely recommended by a urologist -- that's what they are skilled at; that's what they do. There are plenty of alternative treatments. Do your research. Maybe check out a few Dr Scholz videos on Youtube or get his book "Invasion of the Prostate Snatchers".

[pd63 in reply to Hidden]

No prostatectomy for me, other non removal treatments are ok with me but no hormone