Updated this with the first randomized trial data:
More evidence for salvage whole pelvi... - Advanced Prostate...
More evidence for salvage whole pelvic radiation after positive lymph nodes have been detected
Are there any studies evaluating the option of laproscopic removal of cancerous pelvic lymph nodes prior escalating to bathing the entire pelvis with radiation?
I guess you didn't read the article.
I tried. I'll try again.
Not so easy on a phone.
I went back and I still don't see it. Though admittedly your writing can sometimes be a bit heavy for me to digest.
So I did searches on "surg" and "ectomy".
Certainly nothing about lymphectomies, endoscopic or otherwise.
Unless you are confusing biopsies and/or prostatectomies for endoscopic lymphectomies.
????
Can someone else read the article and point out what I may be missing?
The very first bullet point:
• All patients had 1-4 positive PLNs found via PLND, most had 1 positive PLN
PLND is defined in the first paragraph:
Is it still worthwhile to attempt salvage radiation (SRT) after positive pelvic lymph nodes (PLN) have been pathologically detected (stage pN1)? Traditionally, patients with PLN dissection (PLND)-diagnosed pN1 prostate cancer have been considered to have incurable systemic disease.
"A pelvic lymph node dissection (PLND) is surgery to remove the lymph nodes from the. pelvis."
hystersisters.com/vb2/artic...
Ahhh, got it. Thanks
I have been recommended to have a 'Sabre' treatment with a MR Linac machine which is capable of targeting a tumor on a lymph node in the pelvic region and 'zapping'it
The tumor was diagnosed after a petscan . The cancer was very close to the uter hence the reason for the use of an upgraded MR Linac machine!! (UK)
It is OK to give a boost dose to the single lymph node, but it is not OK to only treat that single lymph node. Where there is one that can be seen on a PET scan, there are many more that are too small to be seen in the pelvic lymph node region.
prostatecancer.news/2020/12...
The same MR Linac can be used to treat the entire pelvic lymph node area. You will also require 2 years of hormone therapy (ADT+Zytiga).
great update Thank you
Thank you. I actually start IMRT this coming week, and this is further evidence to help me feel better about everything
Thank you TA. I am interested in hearing from those who have had this ⬆️ particular treatment (whole pelvis, salvage— what’s mentioned in this linked article in TA’s post) about the acute and late urinary, bowel, and sexual toxicity you’ve experienced. And, what kind of scans and planning were done with your RO to minimize any of these toxicities. There is some writing about MRI and other imaging to avoid damage caused by uncontrollable movement (eg intestines) during treatment.
As many people as I have seen that have had RP and then had progression year(s) later I would think this should be SOC.