Interesting new research on why ARI d... - Advanced Prostate...
Interesting new research on why ARI drugs like Xtandi fail
So after reading, it seems to me we need to give it everything we can to block every path way. Why not incorporate the off label drugs too… fool this horrible beast. My poor husband, I am always giving him my green tea and anything else I can… why not. The more I read about high dose vitamin c infusions at least twice a week can only help. Again, how can it hurt you, except make you run out of money. Oh God bless us all!
It does fail. But for me it has kept me going for 5 years after the first 6 months of chemo. Larry_Dammit is more than 5 years, and some more have had great response also. Zytiga or Xtandi do not work well for some. But for those that it works well for we wait for the shoe to drop. I was told incurable. I have faced those facts long ago. The grim fact is: after Xtandi fails me, I will be going on the downward curve. My goal is to be taken out by something other than prostate cancer. Left my primary doctor speachless. My reality is different than his.
monte, your post is making me feel better.. thank you, my husband started xtandi today.
You may already know, but most of us take our 4 horse pills at bed time. That may help with the fatigue issue. 2 pills, swallow of water, 2 pills swallow of water. One more extra swallow of water and then neigh, neigh. Deep breathing and goodnight.
no I forgot about that! monte he just took it an hour ago. Lol he will be asleep for the eagles game❤️Thankyou for the heads up!
have you tried one pill with a meal?
Hey monte you got a lot of options if or when Xtandi stops working. Im kinda sorta on your path but started later and treatments aren't lasting as long.
I had chemo then year later Zytiga then a month ago Zytiga stopped working after one year. I knew the day would come and I had prepared for some of the treatment decisions I would have and knew that having a free ride on the chemo and Zytiga would be the best part of the ride. After that a lot of choices and I think things move quicker or to be blunt burn thru treatments quicker. But anyway a lot of choices after Xtandi or Zytiga. Hold that chin up friend lol.
taking jevtana, abi failed after a year and half, xtandi failed after 3 months, that led to mets on liver and bladder, on second treatment, first treatment dropped PSA 20 points, after this then on to pluvicto, can take these treatments for long term if they work what after theses two is left ?
Well depends on the particulars of your cancer as to what to choose after each treatment eventually runs out of steam. Sorry but it would be hard for me or anyone here probably to answer actually but of course as you move along in this journey keep the forum informed.
LOL. Every time I hold my chin up it's an upper cut coming my way. I'll keep an eye on your progress. BOW. That's best of wishes.
my husband incurable too… I’m sorry Monte
Life is incurable. We are just facing it before we expected to. Yes, it hits us in the face like a sledge hammer. I have lost a son, a daughter and a wife. The grief was overwhelming. But now I can laugh and make jokes again. Just what they would have wanted me to do. The road to despair and depression leads nowhere. Take your husband out for a nice dinner. Don't talk cancer. Enjoy each day. With luck, it may be years. Don't force green tea or anything else on hubby if he doesn't want it. He will resent it. Ask him what he wants to eat, but don't treat him like he is a baby or has some incurable disease. Many of us have to force ourselves to eat. We are anemic. We are not really hungry. Until we start eating. And then we start to enjoy life again. And he has you.
monte, thank you for this good advise! I am thinking about what a strong man you must be.
just an incidental: so sorry for your terrible losses. Glad you have recovered from the grief.
Thank you, kind Sir.
I totally agree try everything if you have quality of life. If not maybe the Lord will bless you with a quick heart attack so you don’t have to die miserable death. It is all in God’s hands so keep the faith my friends🙏🙏🙏
I think you are being funny ?
On the gasoline metaphor: In case of prolonged shortages and high prices at the pump, people will eventually move to electric vehicles and solar power (read castration resistance PCa). On the flip side, gasoline abundance and rediculously low prices will revive 4lt V6 engines (read rapid progression). The trick here is to adjust supply vs demand to a level affordable for the bulk of motorists. This is what I am trying to implement via my Bicalutamide maneuvers.
I have solar panels and an electric car (hybrid). Maybe I'm one up on this deal or no deal situation.
I’m with you!
coal
pickleboy… where you from lol
Horsham…. Hi neighbor!!
thats very intresting reading.
The body finds ways to solve tricks n puzzles.
Maybe keep switching therapies???
I am in Old City, half mile to Independence Hall
Aw Broad street run and Philie marathon.. the best!!
As the article first stated “While successful in most cases”
I fall in that category. Very happy with the results of Xtandi.
As with my MO and Urology Dr.
Does this research suggest intermittent use of ARI drugs to combat the tendency of cancer cells to become castrate resistant? I skimmed the article.
XTANDI beginning to fail
after xtandi and zytiga fail- 
What's next after Xtandi fails?
