Muscadine MPX

[lewicki]

Where can I get Muscadine in powder form to be able to take 4000 mg daily. Karmanos has a stage 11 trial for this.

[Tall_Allen]

"Compared with placebo, MPX did not significantly prolong PSADT in BCR patients over two different doses"

ncbi.nlm.nih.gov/pmc/articl...

[lewicki in reply to Tall_Allen]

Karmanos must not know this has been done?

[lewicki in reply to Tall_Allen]

Dosage at Karmanos is 4000 mg not 500 mg.

[Tall_Allen in reply to lewicki]

It was done at Karmanos.

"Muscadine Plus Grape Skin Extract (MPX): Phase I Dose-escalation starts at 500mg daily for 1 cycle (28 days), then increased to 1000mg for 2nd cycle, then increased to 2000mg daily for 3rd cycle, then increased to 3000mg daily for 4th cycle, then increased to maximum dose of 4000mg daily for final cycle. Pills given by mouth once daily for 28 days per cycle."

[pjoshea13]

"Compared with placebo, MPX did not significantly prolong PSADT in BCR patients over two different doses. Exploratory analysis revealed a patient population with potential benefit that would require further study."

{"In a preplanned exploratory analysis, PSADT pre-to-post increase was significant in the 27 (26%) genotyped patients with SOD2 Alanine/Alanine genotype (rs4880 T>C polymorphism) on MPX"}

pubmed.ncbi.nlm.nih.gov/291...

-Patrick

[lewicki]

Ongoing trial at Karmanos 2018-173 NCT 03535675 The Nap Trial I think this is a new trial? Phase 111

[lewicki]

I found a place that will sell a kilo for $120 in powder. No caps