Does anyone know anything about this drug?
Seviteronel (VT-464) - Durham's Innocrin Nabs FDA Fast Track OK for Prostate Cancer Drug
ncbiotech.org/news/durhams-...
"The FDA has granted a fast track designation for Innocrin’s seviteronel (VT-464) for the treatment of patients with metastatic castrate-resistant prostate cancer (CRPC). Fast tracking is a way the FDA speeds its review of promising new therapies targeting unmet medical needs."
Kind of similar to abiraterone but it does not require to add prednisone. The clinical trials are "completed".
It hasn't yet announced any Phase 3 trials. It is a long way off.
There appear to be quite a few drugs out there that many people who have exhausted SOC treatments desperately need, but aren't aware of! What's maddening and frustrating is to discover that many oncologists aren't willing to go past SOC to help! So the poor patient and his/her stressed out advocate/s are the ones who have to go out there to find these possible treatments on their own - and hope and pray they can get them in time!! Sorry.... I needed to vent.....
It's not that anyone is "not aware of" them - I have a long list of clinical trials. You can easily look at clinicaltrials.gov. The issue is that we don't yet know if any of them have any effect, or if they do, whether they might make the patient so sick that he will die sooner if he takes it. The SOC is very good, and the FDA has been rushing approval. For some drugs , the FDA has even allowed the drugs to be used without proof that they extend life. The FDA has also shown great flexibility in allowing new indications for drugs that have a known history of safety.
If you want to try a new drug before it's approved, it's easy - enroll in a clinical trial. If you want to repurpose an already approved drug, most oncologists I've met are willing as long as it is safe.
What I meant is that it's disheartening when your oncologist doesn't at least suggest looking into clinical trials after telling you there's nothing more he can do. Instead, he's just throwing in the towel.
Thank God for this web site and posters like you who have been incredibly helpful while providing valuable and inspiring information!
Prostate cancer - no metastases - treat now with repurposed drugs?FDA Approves Darolutamide Plus Docetaxel for Metastatic Hormone-Sensitive Prostate Cancer
Apalutamide Submitted to FDA for Treatment of Metastatic Castration-Sensitive Prostate Cancer
FDA Clearance of FK-PC101, a Novel Personalized Prostate Cancer ImmunotherapyONCT-534 Earns FDA Fast Track Designation in R/R Metastatic CRPC
