Understanding measurements

[marykg46]

So many knowledgeable people on this site. I wondered if anyone can help me understand the measurements given on a PSMA. For example .. SUV Max 5.8, 10.45, 8.31...... what exactly do these measurements tell..?

[6357axbz]

I’m pretty new here and can’t answer your questions but I’m sure someone who can will respond to you shortly. Here is a link of abbreviations you may find helpful:

prostatecancerinfolink.net/...

[Darryl Partner in reply to 6357axbz]

Here’s a more comprehensive list. healthunlocked.com/advanced...

[marykg46 in reply to Darryl]

Thank you Darryl.

[GP24]

The more SUV, the more cancer has been detected in the lesion.

en.wikipedia.org/wiki/Stand...

[marykg46 in reply to GP24]

Very helpful. Thank you.

[snoraste]

If I'm not mistaken, SUV is a measure of "avidity" of PSMA expression of cells. You can have low "avidity" because a) you have low burden of disease, or b)non-PSMA expressive cancer cells. I'm told, as a rule of thumb, they are looking for ~20 SUV before doing Lu177 treatment (this info might be old though, check with your MO)

[marykg46 in reply to snoraste]

This makes it clearer. Thank you.

[Tall_Allen]

It is a measure of how much of the radio-indicator was taken up by the tissue. It means nothing by itself - it should only be interpreted in relation to expected values. There should be an accompanying radiologist's report explaining where it is important and where it isn't.

[marykg46 in reply to Tall_Allen]

Thank you. Helpful information.