Darolutamide and Apalutamide

[Blair77]

Any ideas when patients will have access to these drugs?

[Hidden]

There have been some preliminary results published in the Darolutamide trials, although no details. Bayer is going to be filing soon for FDA approval:

pharmaphorum.com/news/bayer...

Apalutamide is already approved for nonmetastatic castrate resistant prostate cancer.

[Pmann]

I have been on apalutamide for just over two months now. Working so far on lowering psa with minimal side effects. Have muscle soreness and slight elevation in BP.

[mcp1941]

I have been on Erleada for 7 months and saw a drop in PSA after the first month. Next three blood draws showed PSA increasing. MO keeping me on Erleada because that is what they did during the trials for those failing Erleada. I'm in my 23rd year fighting PCa with no detectable mets.

[j-o-h-n in reply to mcp1941]

23 years? Holy Shit.... Good for you...May you add 23 years more. Some guys have all the fun...

Good Luck, Good Health and Good Humor.

j-o-h-n Sunday 02/03/2019 5:43 PM EST

[mcp1941 in reply to j-o-h-n]

Thank you John. Other than feeling very tired all the time I have no indications of PCa however MO thinks cancer is morphing into neuroendocrine cancer. If true, that really sucks.

[j-o-h-n in reply to mcp1941]

Hopefully it's not true... You have 23 years more to go....

Good Luck, Good Health and Good Humor.

j-o-h-n Sunday 02/03/2019 10:34 PM EST