Latitude Trial

[miina]

Trial included those with bone and visceral involvement

Do any of you brilliant researchers know where details of the type and extent of visceral mets that participants had prior to enrolement

[Tall_Allen]

That info is probably in the appendix, which I haven't seen. The patients were required to have at least two of the three following high-risk factors:

•a Gleason score of 8 or more

• at least three bone lesions

• the presence of measurable visceral metastasis

[tango65]

Three or more visceral metastases. But they could enter in the trial if they had less than 3 visceral metastases but they had Gleason 8 or more and 3 or more bone metastases.

ascopost.com/News/55700

"LATITUDE is a multinational, randomized placebo-controlled phase III clinical trial of men with newly diagnosed, high-risk metastatic prostate cancer who had not previously received androgen-deprivation therapy. All patients had at least two of three risk factors: Gleason score of 8 or more, 3 or more bone metastases, or 3 or more visceral metastases".