ART Low detectable uPSA after prostat... - Active Surveillan...

Active Surveillance - Prostate Cancer

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ART Low detectable uPSA after prostatectomy – watch or treat? 2004

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Undetectable PSA” (419 patients)

0.03 ng/ml or less

“Low detectable, stable PSA” (93 patients)

PSA greater than 0.03 and less than 0.2 ng/ml

No two subsequent increases in PSA, and/or

PSA velocity less than 0.05 ng/ml/yr

“Low detectable, unstable PSA” (54 patients)

PSA greater than 0.03 and less than 0.2 ng/ml

Two subsequent increases in PSA, and/or

PSA velocity of 0.05 ng/ml/yr or greater

The 7-year recurrence-free survival rates for the three groups were found to be:

95 percent in the “undetectable PSA” group

94 percent in the “low detectable, stable PSA” group

37 percent in the “low detectable, unstable PSA” group

Fewer than a third of patients with a post-prostatectomy biochemical recurrence experienced systemic progression, and it takes a median of 8 years for distant metastatic progression, and 13 years for mortality to occur,

prostatecancerinfolink.net/...

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