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Docetaxel
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Lutetium-617 vs Lutetium-TLX591 plus Xyandi after Zytiga failure. Question from Australia.
Previous
Docetaxel
, EBRT and Stereotactic. 68 yrs old hoping to make it to 70. Any suggestions, information or questions greatly appreciated. Mark Emrys
Previous
Docetaxel
, EBRT and Stereotactic. 68 yrs old hoping to make it to 70. Any suggestions, information or questions greatly appreciated. Mark Emrys
MarkEmrys
in
Advanced Prostate Cancer
2 years ago
Vmat rapid arc radiotherapy
My London RO also has me lined up for radiotherapy to the prostate but said ERBT 20 fractions of VMAT rapid arc being suggested by Finland so would need to get a flat for a month ( commuted so far) 2nd of 3
Docetaxel
bombs today.
My London RO also has me lined up for radiotherapy to the prostate but said ERBT 20 fractions of VMAT rapid arc being suggested by Finland so would need to get a flat for a month ( commuted so far) 2nd of 3
Docetaxel
bombs today.
Brysonal
in
Advanced Prostate Cancer
2 years ago
Rounding the corner of 3 yrs on Keytruda
Very brief summary: Dx at 46 stage 4 Gleason 9; ADT; Chemo round 1 (etoposide/cisplatin) concurrent with pelvic radiation; Zytiga; High T clinical trial; enzalutamide; targeted radiation on bone Mets; chemo round 2 (
docetaxel
)….
Very brief summary: Dx at 46 stage 4 Gleason 9; ADT; Chemo round 1 (etoposide/cisplatin) concurrent with pelvic radiation; Zytiga; High T clinical trial; enzalutamide; targeted radiation on bone Mets; chemo round 2 (
docetaxel
)….
Chugach
in
Advanced Prostate Cancer
2 years ago
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Why would PSA drop now?
When Jeff was in between
Docetaxel
failing and his actively starting Zytiga, his PSA dropped. Now, Jeff is in between carboplatin/cabazitaxel failing and who knows what’s next and his PSA dropped from 365 to 275. I’m baffled. Twice now in between treatments, his PSA has dropped.
When Jeff was in between
Docetaxel
failing and his actively starting Zytiga, his PSA dropped. Now, Jeff is in between carboplatin/cabazitaxel failing and who knows what’s next and his PSA dropped from 365 to 275. I’m baffled. Twice now in between treatments, his PSA has dropped.
Pancake_Lefse
in
Advanced Prostate Cancer
2 years ago
Nivolumab+docetaxel trial
My MO suggested me to participate in Nivolumab/placebo +
docetaxel
trial, Phase 3. I checked the results of Phase 2, and, honestly, I was not very impressed with results. I found no big difference between effectiveness of this combo and
docetaxel
only.
My MO suggested me to participate in Nivolumab/placebo +
docetaxel
trial, Phase 3. I checked the results of Phase 2, and, honestly, I was not very impressed with results. I found no big difference between effectiveness of this combo and
docetaxel
only.
Catfish21
in
Advanced Prostate Cancer
2 years ago
ADT+docetaxel first impressions, adding darolutamide
First dose of
docetaxel
wasn't too bad. Immediately after infusion I felt fine and could even have driven myself home but took a taxi. Had some headache and tiredness a couple of days later, but that was it.
First dose of
docetaxel
wasn't too bad. Immediately after infusion I felt fine and could even have driven myself home but took a taxi. Had some headache and tiredness a couple of days later, but that was it.
Oldie68
in
Advanced Prostate Cancer
2 years ago
Starting Xofigo RA 223
My question is - have any of you tried Xofigo after
Docetaxel
and did you have any luck with it. I am feeling the best I have felt in a year after the chemo. We sure always appreciate all of your input. Thanks - Tom
My question is - have any of you tried Xofigo after
Docetaxel
and did you have any luck with it. I am feeling the best I have felt in a year after the chemo. We sure always appreciate all of your input. Thanks - Tom
Hidden
in
Advanced Prostate Cancer
2 years ago
Pluvicto plus Xtandi
I’ve run the gambit of Bicalutamide,
Docetaxel
, Abiraterone, Cabazitaxel, still taking Lupron and Zometa. At the beginning of June I started Enzalutamide (Xtandi) 4x40 mg. After about a month I started having issues with fatigue, loss of appetite, nausea and dizziness.
I’ve run the gambit of Bicalutamide,
Docetaxel
, Abiraterone, Cabazitaxel, still taking Lupron and Zometa. At the beginning of June I started Enzalutamide (Xtandi) 4x40 mg. After about a month I started having issues with fatigue, loss of appetite, nausea and dizziness.
Rondief
in
Advanced Prostate Cancer
2 years ago
Docetaxel and headaches?
I had Dexamethasone before and after the
Docetaxel
but have Prednisolone on normal days.
I had Dexamethasone before and after the
Docetaxel
but have Prednisolone on normal days.
konichiwa12
in
Advanced Prostate Cancer
2 years ago
VERU-111 (sabizabulin)
Taxanes (like
docetaxel
and cabazitaxel) [i]stabilize[/i] the tubulin so the cancer cell cannot undergo fission into two cells. Cells that are trying to actively replicate die. Sabizabulin [i]disrupts[/i] the tubulin so that the cell cannot use it to form a stable cell.
Taxanes (like
docetaxel
and cabazitaxel) [i]stabilize[/i] the tubulin so the cancer cell cannot undergo fission into two cells. Cells that are trying to actively replicate die. Sabizabulin [i]disrupts[/i] the tubulin so that the cell cannot use it to form a stable cell.
Tall_Allen
in
Advanced Prostate Cancer
2 years ago
Chemotherapy and Gout
After 8 doses of
Docetaxel
& 3 of Carboplatin, my partner has had two painful bouts of gout. He watches his diet carefully (pretty much has eliminated red meat & alcohol). is there a connection with chemo & gout? Despite asking his PP and MO, neither mentioned any.
After 8 doses of
Docetaxel
& 3 of Carboplatin, my partner has had two painful bouts of gout. He watches his diet carefully (pretty much has eliminated red meat & alcohol). is there a connection with chemo & gout? Despite asking his PP and MO, neither mentioned any.
julyturqsee
in
Advanced Prostate Cancer
2 years ago
Should Early Use of Chemotherapy Be Avoided in the Treatment of Metastatic Prostate Cancer?
"According to the evidences so far, including this study,
docetaxel
should be recommended as second-line treatment for metastatic CRPC patients who received first-line ARPI. However,
docetaxel
is selected as second-line treatment only for limited patients in real-world clinical practice.
"According to the evidences so far, including this study,
docetaxel
should be recommended as second-line treatment for metastatic CRPC patients who received first-line ARPI. However,
docetaxel
is selected as second-line treatment only for limited patients in real-world clinical practice.
pjoshea13
in
Advanced Prostate Cancer
2 years ago
ADT + Abi + Docetaxel for metastatic prostate cancer?
Would be grateful to hear people's thoughts on the triple-therapy (ADT+Abi+
Docetaxel
) in his situation. Thoughts? (https://ascopost.com/news/september-2021/peace-1-and-stampede-trials-abiraterone-acetate-plus-prednisolone-in-prostate-cancer/)
Would be grateful to hear people's thoughts on the triple-therapy (ADT+Abi+
Docetaxel
) in his situation. Thoughts? (https://ascopost.com/news/september-2021/peace-1-and-stampede-trials-abiraterone-acetate-plus-prednisolone-in-prostate-cancer/)
Shanti1
in
Advanced Prostate Cancer
2 years ago
My Jevtana/Carboplatin results to date. Part Two.
It’s because of you that I was started on this combo after 7 previous chemo infusions (3
Docetaxel
, 4 Jevtana) with poor results.
It’s because of you that I was started on this combo after 7 previous chemo infusions (3
Docetaxel
, 4 Jevtana) with poor results.
Mount_Rainier
in
Advanced Prostate Cancer
2 years ago
Daralutamide and Survival in Metastatic, Hormone Sensitive Prostate Cancer
CONCLUSIONS In this trial involving patients with metastatic, hormone-sensitive prostate cancer, overall survival was significantly longer with the combination of darolutamide, androgen-deprivation therapy, and
docetaxel
than with placebo plus androgen-deprivation therapy and
docetaxel
, and the addition
CONCLUSIONS In this trial involving patients with metastatic, hormone-sensitive prostate cancer, overall survival was significantly longer with the combination of darolutamide, androgen-deprivation therapy, and
docetaxel
than with placebo plus androgen-deprivation therapy and
docetaxel
, and the addition
Graham49
in
Advanced Prostate Cancer
2 years ago
How to cope and combat Docetaxel side effects without compromising its effectiveness
Is there are role for Naturopathic therapies to help with se of
docetaxel
? Does anyone have experience with these practitioners, good or bad? Any suggestions on what I can do to help with my recovery from
docetaxel
will be helpful and taken seriously. Thank you
Is there are role for Naturopathic therapies to help with se of
docetaxel
? Does anyone have experience with these practitioners, good or bad? Any suggestions on what I can do to help with my recovery from
docetaxel
will be helpful and taken seriously. Thank you
Grateful4this
in
Advanced Prostate Cancer
2 years ago
At what point - stereotactic treatment versus chemo
He is uncertain where to go straight to
docetaxel
or zapping the 4 most active spots (and maybe more). He will be getting a consult to help him decide. My question - what is the typical cut off for making this choice?
He is uncertain where to go straight to
docetaxel
or zapping the 4 most active spots (and maybe more). He will be getting a consult to help him decide. My question - what is the typical cut off for making this choice?
Arthur479
in
Advanced Prostate Cancer
2 years ago
Chemo
My husband has had 6 rounds of
Docetaxel
, 3 rounds of jentava and now two rounds of Jentava along with Carboplatin. None have even touched the psa and some progression on the scans. This is taking a huge toll. He has been on Zytiga, Lynparza, Keytruda now the chemo. Just asking opinions.
My husband has had 6 rounds of
Docetaxel
, 3 rounds of jentava and now two rounds of Jentava along with Carboplatin. None have even touched the psa and some progression on the scans. This is taking a huge toll. He has been on Zytiga, Lynparza, Keytruda now the chemo. Just asking opinions.
Fight11
in
Advanced Prostate Cancer
2 years ago
PSA rising a concern? Mets to bones, livers, lungs and lymph nodes
He started Firmagon and then on Zoladex and then 6 cycles of
docetaxel
which finished at the end of November. His mets in general have reduced significantly in both the liver and lungs. His PSA was <0.02 in November, taken on the same day as his last cycle of
docetaxel
.
He started Firmagon and then on Zoladex and then 6 cycles of
docetaxel
which finished at the end of November. His mets in general have reduced significantly in both the liver and lungs. His PSA was <0.02 in November, taken on the same day as his last cycle of
docetaxel
.
dch1953
in
Advanced Prostate Cancer
2 years ago
Next Move
Guidelines point to
docetaxel
or Jevtana, but still stuck on those neuropathy side effects. I feel that if I see increased neuropathy from the chemo it will be the end of my mobility, as I have gone from cane to rollator since the cancer was diagnosed.
Guidelines point to
docetaxel
or Jevtana, but still stuck on those neuropathy side effects. I feel that if I see increased neuropathy from the chemo it will be the end of my mobility, as I have gone from cane to rollator since the cancer was diagnosed.
Kentucky1
in
Advanced Prostate Cancer
2 years ago
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