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Dexmedetomidine attenuates motor deficits via restoring the function of neurons in the nigrostriatal circuit in Parkinson's disease - mice
Dexmedetomidine attenuates motor deficits via restoring the function of neurons in the nigrostriatal circuit in Parkinson's disease model mice https://pubmed.ncbi.nlm.nih.gov/35150656/ Dexmedetomidine (DEX) is a sedative and analgesic drug.
Dexmedetomidine attenuates motor deficits via restoring the function of neurons in the nigrostriatal circuit in Parkinson's disease model mice https://pubmed.ncbi.nlm.nih.gov/35150656/ Dexmedetomidine (DEX) is a sedative and analgesic drug.
Hidden
in
Cure Parkinson's
2 years ago
Petition to grant visas to Ukrainian refugees
Please sign and share if you agree https://petition.parliament.uk/petitions/609530 I’m so ashamed of the Home Office’s inhumanity towards these exhausted and traumatised people Ps: a report from Mark Easton, the BBC’s Home Editor in Calais: “On Monday, one family followed by the BBC was sent from building
Please sign and share if you agree https://petition.parliament.uk/petitions/609530 I’m so ashamed of the Home Office’s inhumanity towards these exhausted and traumatised people Ps: a report from Mark Easton, the BBC’s Home Editor in Calais: “On Monday, one family followed by the BBC was sent from building
Hidden
in
Lung Conditions Community Forum
2 years ago
Pain!!
Hi, So I’m month 4 off birth control (spent 10yrs on it). The symptoms are becoming more obvious now. Currently on my period and I’m getting really bad shooting pains that feel like they are going from my vagina up into my uterus and having a pulling pain in my stomach. The shooting pains are like some
Hi, So I’m month 4 off birth control (spent 10yrs on it). The symptoms are becoming more obvious now. Currently on my period and I’m getting really bad shooting pains that feel like they are going from my vagina up into my uterus and having a pulling pain in my stomach. The shooting pains are like some
bumble_96
in
Endometriosis UK
2 years ago
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Pip difficulties
Hi all, I was just wondering whether anyone has had difficulties claiming pip for fibromyalgia and osteoarthritis. I have been refused and I am going through a mandatory reconsideration because I feel like I am being disregarded. Any help or advice would be much appreciated.
Hi all, I was just wondering whether anyone has had difficulties claiming pip for fibromyalgia and osteoarthritis. I have been refused and I am going through a mandatory reconsideration because I feel like I am being disregarded. Any help or advice would be much appreciated.
LD58
in
Fibromyalgia Action UK
2 years ago
Naproxen and kidney insufficiency
I have kidney insufficiency (51%), aged 70. I also have rheumatoid arthritis in my feet and is very painful. Before I ask my doctor, is it advisable for me to take Naproxen and PPI's?
I have kidney insufficiency (51%), aged 70. I also have rheumatoid arthritis in my feet and is very painful. Before I ask my doctor, is it advisable for me to take Naproxen and PPI's?
jacartist
in
Lung Conditions Community Forum
2 years ago
Researchers discover the cause of lupus
Related Stories New vaccine prevents rheumatoid
arthritis
, research study finds Vegan diet eases
arthritis
pain
, finds new study Scientists discover link between gut microbes and
arthritis
To confirm that the mutation causes lupus, the team used CRISPR gene-editing to introduce it into mice.
Related Stories New vaccine prevents rheumatoid
arthritis
, research study finds Vegan diet eases
arthritis
pain
, finds new study Scientists discover link between gut microbes and
arthritis
To confirm that the mutation causes lupus, the team used CRISPR gene-editing to introduce it into mice.
Thick_Blood
in
LUpus Patients Understanding and Support
2 years ago
Is anyone still taking Co-proxamol pain killer?
Hi there I've just given some quotes to a journalist from the Mail on Sunday about my experience of having to stop taking co-proxamol when it was taken off the market as a regular pain killer used by many for managing different types of pain. At that time I was getting it as a named patient from my GP
Hi there I've just given some quotes to a journalist from the Mail on Sunday about my experience of having to stop taking co-proxamol when it was taken off the market as a regular pain killer used by many for managing different types of pain. At that time I was getting it as a named patient from my GP
Ailsa-NRAS
NRAS
in
NRAS
2 years ago
Anyone else in the diagnosis stage just feeling exhausted and mentally drained?
I first went to a doctor about pains way back when I was either 17 or 18. They were put down to period pains and that was it. But they kept happening. I just ignored them, thinking I was just imagining it or overreacting. But in November last year they got unbearable. Went back to the doctors - a new
I first went to a doctor about pains way back when I was either 17 or 18. They were put down to period pains and that was it. But they kept happening. I just ignored them, thinking I was just imagining it or overreacting. But in November last year they got unbearable. Went back to the doctors - a new
CaledoniaSloth91
in
Endometriosis UK
2 years ago
Fibro diagnosis - and a prescription to do karate!
After having my NHS rheumatology appointment cancelled twice in three months, then unsuccessfully trying to get a private consultation (turned out the hospital I wanted to go to don't actually do private consultations), I finally got seen by a visiting rheumatologist at my local hospital this weekend
After having my NHS rheumatology appointment cancelled twice in three months, then unsuccessfully trying to get a private consultation (turned out the hospital I wanted to go to don't actually do private consultations), I finally got seen by a visiting rheumatologist at my local hospital this weekend
mjrminor
in
NRAS
2 years ago
Just wondering……..
I’ve started to slowly lose a little bit of weight, but a big change is the reduction in my
pain
levels. Drugs are keeping the
arthritis
stable. So now I’m wondering if thyroid, fibro & cholesterol are all inter connected 🤷♀️🤷♀️.
I’ve started to slowly lose a little bit of weight, but a big change is the reduction in my
pain
levels. Drugs are keeping the
arthritis
stable. So now I’m wondering if thyroid, fibro & cholesterol are all inter connected 🤷♀️🤷♀️.
NannyNooNoo
in
Fibromyalgia Action UK
2 years ago
Anyone had this
Hi girls anyone experiencing left,right sides stomach back endometriosis pain bad even when u try move or get up it hurts so much to point u cant move even a slightest bit because if u do ur screaming in pain if u coughed, sneeze or anything? Plz I'm in so much pain and everytime I try move I'm just
Hi girls anyone experiencing left,right sides stomach back endometriosis pain bad even when u try move or get up it hurts so much to point u cant move even a slightest bit because if u do ur screaming in pain if u coughed, sneeze or anything? Plz I'm in so much pain and everytime I try move I'm just
nikkimatt2019
in
Endometriosis UK
2 years ago
PAIN EVERYDAY - What to do
My pain has been so frequent recently making me vomit and dizzy. I’m under a lot of stress with uni atm and many so I know my body is exhausted. I’m trying to stop taking strong pain killers like tramadol but sometimes the pain is unbearable I can’t even walk or get up. I have not had an operation yet
My pain has been so frequent recently making me vomit and dizzy. I’m under a lot of stress with uni atm and many so I know my body is exhausted. I’m trying to stop taking strong pain killers like tramadol but sometimes the pain is unbearable I can’t even walk or get up. I have not had an operation yet
Littlebug77
in
The Endometriosis Foundation
2 years ago
Pain in feet
By the way I had psoriatic
arthritis
but been
pain
free for years. This sudden pain is worrying me. Can anybody understand or even give ideas what they think it could be. Thanks
By the way I had psoriatic
arthritis
but been
pain
free for years. This sudden pain is worrying me. Can anybody understand or even give ideas what they think it could be. Thanks
Junny1
in
Pain Concern
2 years ago
Symptoms abate when the immune system has something else to deal with ?
Hi. I’ve broken my ankle and was expecting that with the PMR too, using crutches was going to be very painful with my shoulders and also shuffling upstairs on my bum using good leg and arms for leverage. In fact. I’ve not felt a twinge from PMR since doing it two weeks ago today. I’ve stayed on my
Hi. I’ve broken my ankle and was expecting that with the PMR too, using crutches was going to be very painful with my shoulders and also shuffling upstairs on my bum using good leg and arms for leverage. In fact. I’ve not felt a twinge from PMR since doing it two weeks ago today. I’ve stayed on my
Buttonshutton
in
PMRGCAuk
2 years ago
Loosing control
Hello everybody, hope everyone is going well, I have fibromalagia for 15 years now, chronic anemia,thyroid disease, vitamin D deficiency, B12 deficiency, chronic hip
pain
, osteomalacia,
arthritis
and restless legs, I would like to ask if someone of you is having like you walk for 2 minutes you don't
Hello everybody, hope everyone is going well, I have fibromalagia for 15 years now, chronic anemia,thyroid disease, vitamin D deficiency, B12 deficiency, chronic hip
pain
, osteomalacia,
arthritis
and restless legs, I would like to ask if someone of you is having like you walk for 2 minutes you don't
Diana29
in
Fibromyalgia Action UK
2 years ago
Losartan Side Effects
Not sleeping great with the bathroom trips at night but now this
pain
and can't get to sleep. I've tested for
arthritis
etc. (I'm 61 yrs.) but all are clear. Any alternatives to this med besides lisinopril (I've tried)? I'm 3a type 2 fsgs so prednisone won't likely help. Thanks.
Not sleeping great with the bathroom trips at night but now this
pain
and can't get to sleep. I've tested for
arthritis
etc. (I'm 61 yrs.) but all are clear. Any alternatives to this med besides lisinopril (I've tried)? I'm 3a type 2 fsgs so prednisone won't likely help. Thanks.
oceansplash
in
Kidney Disease
2 years ago
How is it still an acceptable comment?
Hi there! Hope you’re all doing ok. I went to the doctors this week to discuss new pain medication - I’ve exhausted the options over the last 6 years but have now been told to stop everything and take one tramadol at night as well as paracetamol and ibuprofen. I explained that the paracetamol & ibuprofen
Hi there! Hope you’re all doing ok. I went to the doctors this week to discuss new pain medication - I’ve exhausted the options over the last 6 years but have now been told to stop everything and take one tramadol at night as well as paracetamol and ibuprofen. I explained that the paracetamol & ibuprofen
LuceRM
in
Endometriosis UK
2 years ago
Thank you VRB’s
A special thanks to Oldfloss for her catch up corner, full of support and wonderful musings. So Acknowledge…..Accept….Adapt we’re the words of wisdom I read in the catch up corner the other day! That made me think 🤔 I have a tumour, in my mouth, the biopsy results appointment isn’t til 31st March
A special thanks to Oldfloss for her catch up corner, full of support and wonderful musings. So Acknowledge…..Accept….Adapt we’re the words of wisdom I read in the catch up corner the other day! That made me think 🤔 I have a tumour, in my mouth, the biopsy results appointment isn’t til 31st March
SueAppleRun
60minGraduate
in
Bridge to 10K
2 years ago
Newly Diagnosed - help!
Hello I was actually diagnosed with Lupus a year ago but have been in denial. I now find the pain, fatigue, temp fluctuations and rashes too much and am considering dropping my hours at work. I have been in extremely anxious about taking HCQ and have not taken it believing I can control the RA with pain
Hello I was actually diagnosed with Lupus a year ago but have been in denial. I now find the pain, fatigue, temp fluctuations and rashes too much and am considering dropping my hours at work. I have been in extremely anxious about taking HCQ and have not taken it believing I can control the RA with pain
Becalming
in
LUPUS UK
2 years ago
The scary chronic pains-anxiety-depression-chronic pains cyle
Hello, So I joined a week ago and I've been hesitant to post anything, though I did receive a few "welcome" messages. I didn't have a good experience with anxiety/chronic health group on facebook and I was recommended to try this site. So, are there any of you who suffer from multiple chronic health
Hello, So I joined a week ago and I've been hesitant to post anything, though I did receive a few "welcome" messages. I didn't have a good experience with anxiety/chronic health group on facebook and I was recommended to try this site. So, are there any of you who suffer from multiple chronic health
Louis-T
in
Anxiety and Depression Support
2 years ago
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