Experiences with

Zileuton

I recently heard this medication being mentioned on a US podcast. Does anyone know anything about it and whether it's available here? Any information would very much appreciated.

If patients do not improve with the LTRA after four to six weeks, then zileuton may be added or substituted. In a survey of patients with AERD, respondents identified zileuton as "extremely effective" more often than LTRAs [47].

For anyone interested in this topic but without direct experience of these drugs, below is a brief explanatory extract pinched from the web: '.....Leukotriene receptor antagonists, such as montelukast, zafirlukast, and pranlukast, and 5-lipoxygenase inhibitors, like zileuton and hypericum perforatum,

I started taking zileuton extended release (Zyflo CR) this afternoon because it's a specialty drug and my pharmacy had to locate it. As far as I can tell it's like motelukast, but a super hefty extended dose that prevents the inflammation earlier in the chain.