Experiences with

Xalkori

The FDA based their approval on the results of a clinical trial which found that patients receiving Lobrena went longer before experiencing progression than those who received Xalkori (crizotinib).

The FDA based their approval on the results of the clinical trial ALTA 1L which showed that patients receiving Alunbrig (brigatinib) had a higher chance of responding well to treatment, and went longer periods of time without progression than those receiving Xalkori (crizotinib).

We have an appointment with the oncologist for Thursday of next week and she'll be having a scan done to see if there have been any changes as a result of the Xalkori. It is so difficult. Any feedback is welcome. Thank you in advance. Betty

My sister will be prescribed Xalkori. Has anyone in this group have any experience with it? Thanks in advance!! Betty

I started off with carboplatin and alimta for 2 months, then switched to Xalkori for 7 months, Zykadia for 5 months and then back on Alimta every 3 weeks for a year. After all that, my cancer was inactive and only scar tissue showed wherever my cancer was.

We are pleased that crizotinib (xalkori) has been approved by NICE for use with a sub-group of people affected by lung cancer. It had previously been approved for use in Scotland by the Scottish Medicine Consorium (SMC). This is a new treatment for a small group of patients with ALK+ tumours.

Have you been prescribed crizotinib? We are looking for patient experiences for crizotinib, if you can help you can post here or private message me. This is so we can make a drug submission to the medicines consortium. As a charity our submissions need to include as much patient experience of the drug

I have stage 4 lung cancer which is alk positive - I have had a great run on xalkori - a targeted Hersey but I have now had slight progression.

I was diagnosed with stage 4 lung cancer 14 months ago non small cell squamous - tested positive for ALK mutation in Feb started on Xalkori in April just had 8 week scan results and it shows significant reduction in all tumours. I'm wondering if anyone else here is on it? Susan