Experiences with

Urokinase

(endothelial PAI)Plasminogen activator inhibitor-1 deficiency plasminogen activator inhibitor-2 (PAI2)Inactivates tPA & urokinase (placental PAI) cancer procoagulantPathological factor X activator linked to thrombosis in cancer https://en.wikipedia.org/wiki/Coagulation#Coagulation_factors i

In androgen-independent PCa, urokinase plasminogen activator (uPA) is implicated in cell migration and cancer metastasis. Treatments of PC3 cells with PAC-rich grape seed extract (PAC-GSE) have shown to regulate uPA expression and cell migration in a dose-dependent manner.

Furthermore, Ganoderma inhibition of expression of uPA {urokinase-type plasminogen activator} and uPA receptor (uPAR), as well secretion of uPA, resulted in the suppression of the migration of ...