Guys. Does anybody have any evaluation/views on this drug in terms of effect on brain? My story goes way back maybe 10 years and at the time concerned lots of chronic pain (back, knees). The docs were about to give up when I told them I'd read about the ability of an old anti-depressant to alleviate pain. They gave me a go on it and within a matter of weeks, much of my pain had gone. My own take on it was (and is) that it gives one such a good nights sleep that your body gets a proper chance to repair itself. I admit that I got a little hooked on it and took it for years on and off due to it's marvellous sleep inducing properties. Anyway, then I get PD. I kept on using amitriptyline thinking 'well everyone who gets it seems to complain that they don't sleep, but hey: I have secret weapon that I'm gonna keep using'. But then I researched a bit and I DID find some serious papers from academics tentatively linking long term ingestion of this drug with the start of PD. One might think that there's no issue as that now I HAVE PD, what's there to lose? Maybe the drug could make things worse, but boy do I love 9 hours quality snooze! Any analysis most welcome friends.