Venetoclax Stomach Issues

[difor29]

Hi everyone! I was diagnosed with Extra Nodal Marginal Zone Lymphoma at the end of September’21. I am taking part of a clinical trial that includes Rituxan and Venetoclax. I have already done the ramp up of the Venetoclax, I’m at 800 mg. I’m doing extremely well, my many lumps have almost gone down completely already but after about 5 hours of taking the Venetoclax, I get some pretty crappy stomach pains that are intermittent and last for about 2 hours then I’m fine. I do not have any nausea or diarrhea at all and overall feel great. Anyone else that has or is on Venetoclax have these stomach pains? I’m eating something every 2 hours thinking maybe it’s because I need to have something in my stomach but it doesn’t work. Thanks!!!

[Name-1]

Hi difor29,I had diagnosed of april 2021: MZLnodal/extranodal,after 10 years Dg.CLL/SLL.I had Rituximab+ Chlorambucil 6 cycles.Now ,I have pains i stomach in day and in night as atacs,2-3 h after foods.I try with Famotidin-nothing better.Now I use Digestion (artichok).I think it is better.

Greeting

Olga

[Lynn_healthivibe]

I have no experience with these meds but may I please say thank you for participating in a clinical trial. It is so beneficial to advance the science for others even if there is no direct benefit to you. THANK you!

[difor29 in reply to Lynn_healthivibe]

You are so welcome! Since being on this trial, I feel like I am 25 again…LOL. It’s really working. I have put on 13 pounds already, which is great for me. I lost a lot of weight with the Lymphoma! I just hope and pray that this trial will be the frontline treatment for Marginal Zone Lymphoma 🙏🏻