COVID-19 vaccine and CLL patients: An analysis of the first published results

[NicoleLeukaemiaCare]

Hi all,

A blog uploaded today to the LC website with an overview of the first results of data studying CLL patients and their response to the COVID-19 vaccines.

Key points:

Initial results of a study from Birmingham on vaccine responses of CLL patients has been published.

34% of CLL patients show antibody responses, rising to 75% after two doses, showing the importance of having both doses.

However, CLL patients produced a much smaller quantity of antibodies than healthy people.

Certain groups of patients were less likely to respond, including those on BTK inhibitors.

The study has a number of limitations to be aware of and you should be cautious in using this data to change your behaviour. Seek advice from your haematology care team as necessary.

To read the full piece, go to the LC website.

leukaemiacare.org.uk/suppor...

[PaulaS]

Thanks so much for this, Nicole. Shows that our antibody responses might not be as bad as we'd feared.

Not so good for those on BTK inhibitors though. I'm wondering if they'll now recommend that some of those people (eg me) should come off the BTK before having covid jabs in future...

Paula

[2003UK]

Thanks for the summary Nicole. I was part of the Birmingham study.