Repurposing drugs: in silico screening is effective to help find new interactions

[Maxone73]

In Silico Screening of Multi-Domain Targeted Inhibitors for PTK6: A Strategy Integrating Drug Repurposing and Consensus Docking

mdpi.com/1424-8247/17/1/60

[NPfisherman]

Max,

Thanks for posting.... The idea of using old drugs for cancer continues to build... Zafirkulast (Accolate), a leukotriene receptor antagonist, is a fairly innocuous drug for PTK6 inhibition. I used to give out the sibling, Singulair at work.

This is an interesting aticle on PTK6 and prostate cancer:

ncbi.nlm.nih.gov/pmc/articl...

These are the types of screening needed, and then using them for targeted therapy to slow progression / evolution... A strategy I am working on for myself, but not using Accolate itself... This needs to be an individualized basis...

Don Pescado

[Maxone73 in reply to NPfisherman]

ncbi.nlm.nih.gov/pmc/articl... if it can help!