Doc vs Parkinson's

[Bolt_Upright]

Some people had not seen this so posting it again: youtu.be/cN2ZgSStm7I(Not working as expected?)

[Smittybear7]

Powerful! Thanks for sharing! Why isn't this a priority for Michael j Fox?

[Hidden in reply to Smittybear7]

Bc it won’t scale up easily and be profitable. Just my guess. Are they funding Blue Rock? I don’t think they are. Or Jeanne Loring? I don’t think so.

[Smittybear7 in reply to Hidden]

I am not familiar with either of those. Could you explain them? Thank you

[Hidden in reply to Smittybear7]

Other stem cell trials and research.

[HekateMoon in reply to Hidden]

If they cured us all...what would they live of...?🤨😑😒

[BrentDeal in reply to HekateMoon]

The reason Doc stayed hidden for so long and paid for everything himself is so "They" wouldn't be able to shut him down. Now, he's so far ahead, and so wealthy, "they" hopefully can't stop him. He's fighting everyday for clinicals to go faster.

[HekateMoon in reply to BrentDeal]

When i refer to "they" is not doc but the big pharma and their mafias..

[BrentDeal in reply to HekateMoon]

me too.. worried about 'them' as well- Doc is not- he proceeded way too far before they even knew about what he and the team were up to.

[BrentDeal in reply to Hidden]

Hello Hidden- sorry I'm late to this post. my name is Brent Deal, I directed the movie Doc vs Parkinson's. I run Doc's instagram @docvsparkinsons. We are also shocked that none of the large "Parkinson Entities" have given us the time of day.Doc continues to fund everything himself, he continues to get better(slowly but surely) - Doc, Kwang-Soo Kim and Boston Mass General start clinical trials very soon. Not trying to spread false hope.

[Gcf51 in reply to Hidden]

I dislike that Hidden doesn't have a profile. I understand HU not deleting a big pile of their previous posts, but question allowing new post or comments.

Hidden - HU's version of the Borg Collective

[jimcaster in reply to Gcf51]

I might not understand what you're saying, but "Hidden" is the identity of all closed accounts. Although their previous posts and comments still appear, people who close their accounts (and are then identified as "Hidden") are no longer able to make new posts or comments.

[Gcf51 in reply to jimcaster]

The post was May 7th (some 100+ days ago), I will buy that "Hidden" is one of the multitude of the Borg Collective and no longer has an account on HU....

[WinnieThePoo in reply to Gcf51]

Remember. Just because you're paranoid doesn't mean the bastards aren't out to get you

[jimcaster in reply to Gcf51]

If the post was made May 7th, someone commented on or after May 7 while their account was still active. At some point after making their comment(s), they closed their account and their old comments have been identified as being made "Hidden" ever since. They cannot make new posts or comments after closing their account (s).

[reedboat2]

Very inspiring. I had not seen this. Thanks for posting- JG

[BrentDeal in reply to reedboat2]

follow Doc's progress on instagram @docvsparkinsons.He's got a long way to go- but they start clinical trials(after many delays) very soon.

[reedboat2 in reply to BrentDeal]

✅now following on IG. Thanks Brent

[Bolt_Upright in reply to BrentDeal]

I am now following Doc on Instagram! Thank you so much.

Will the movie be available online sometime? I would love to see it.

[JAS9]

I would think that the governments of the wealthiest countries would (or should) gladly pay for the research since if they don't the number of people with PD and AZ and other similar diseases will overwhelm their budgets!

[Boscoejean in reply to JAS9]

I have heard this said about alzheimers as well and it is troubling to think about the challenges to care that are likely upcoming

[Zella23]

Thanks for posting. Really interesting and gives hope!

[Mischl]

This is really encouraging. Thanks for sharing this.

[Dana54]

This is so inspiring, and it gives hope. It's also very heartwarming to see someone that cares about others and still working to help others. Thank you, Bolt!

[BrentDeal in reply to Dana54]

Doc is still fighting for others. He continues to fund everything himself- they start clinical trials (after many delays) very soon. follow on instagram @docvsparkinsons

[Gcf51]

Thanks for posting... I needed that..

Treated with his body’s own stem cells…. Would this treatment be disease specific???

[BrentDeal in reply to Gcf51]

Hi - I'm Brent Deal, director of the movie Doc vs Parkinson's. Right now they are concentrating on Parkinson's but yes... Kwang-Soo Kim's remarkable process of turning someone's own skin cell into an IPSC cell(their own stem cell) will help many other diseases of the brain down the road. Unfortunately- it takes time, years and maybe even decades to go through the FDA process..Doc and Kwang-Soo are fighting as hard as they can to go as fast as they can.

follow Doc's progress on instagram @docvsparkinsons

[Lizzy9 in reply to BrentDeal]

Thank you for the update!!

[Gcf51 in reply to BrentDeal]

I don't and won't use instagram...

[Lizzy9]

Thank you for posting. I wonder what has happened since Doc had this procedure? Are there updates?Thank you again & have a fabulous day!!!

Gail

[Bolt_Upright in reply to Lizzy9]

einnews.com/pr_news/5698193...

"Doc vs Parkinson's is set to be released end of 2022 or early 2023 depending on how the clinical trials proceed. (The clinical trials are set to start in May 2022.)

"We simply don't want to create false hope. It worked on me, but I'm just patient one, The FDA needs to see it work on 20 more." (Doctor George A Lopez)"

[BrentDeal in reply to Lizzy9]

Hi Lizzy- after many delays- Doc and Kwang-Soo are starting clinical trials very soon.follow their progress on instagram @docvsparkinsons

[Manypony]

I’d sure try it

[wifeofparky]

Praying he gets the funding needed to continue the study. One case is a step in the right direction but it is still anecdotal.

[JAS9]

I just went looking (online) for Dr. Kwang-Soo Kim and found him still working at McLean, which is a "Harvard Medical School Affiliate". I know that some colleges and Universities use affiliate corporations in order to build up and spin off profitable businesses from the research they own. Sure, "Doc" added some funding in order to get the project going again, but before that, all of Dr. Kim's work had been funded by Harvard.

I'm pretty sure that that's what's happening here. And if so that's good news! It means that it's being worked on with a goal of bringing it mainstream if and when whatever issues are left to be resolved have been resolved. Usually, this has to do with bringing the costs of the procedures down but can also involve producing stronger results that last longer. So it's not always about profit.

I have hope that it will eventually be widely available, but I haven't found anything that suggests any particular timeline. As for funding, I wouldn't worry about that either:

"The Harvard Management Company returned 33.6 percent on its investments in fiscal year 2021, increasing Harvard's endowment to its unprecedented total of $53.2 billion. Oct 25, 2021"

Harvard is flush, and they get even wealthier by doing things like this.

mcleanhospital.org/video/pe...

[Hidden in reply to JAS9]

When I posted about this and posted the video Bolt reposted, believe I elaborated upon the current state of the trial. And I did a year + ago under an account that is now called hidden. More info has been posted. I just don’t have time to look for it at the moment

[Despe in reply to Hidden]

May 13, 2020 date it was announced. What happened from then until now?

[JayPwP in reply to Despe]

Same question I have

[Bolt_Upright in reply to JayPwP]

einnews.com/pr_news/5698193...

"Doc vs Parkinson's is set to be released end of 2022 or early 2023 depending on how the clinical trials proceed. (The clinical trials are set to start in May 2022.)

"We simply don't want to create false hope. It worked on me, but I'm just patient one, The FDA needs to see it work on 20 more." (Doctor George A Lopez)"

[Hidden in reply to Bolt_Upright]

Last year they were recruiting for the trial. I shared contact info and links at that time. No time to dig it up at the moment just FYI. I know some HU PWP then inquired. I suspect that one was accepted but never heard back from him.

[JAS9 in reply to Despe]

This is the response I just got back. Nice of him to respond.

"My name is Brent and I did the video you saw as well as directed the movie on Doc that will be released end of this year.

There is good news and bad news- we’ll start with the bad news- Doc and Kwang-Soo are still at least 3 years away from full FDA approval (making it available to the public).

The clinical trials are approved so 10 more will be treated soon. They have been selected already.

Doc continues to get better as the cells in his head are multiplying and creating dopamine- his progress is slow but he is progressing- he is the first person to reverse the symptoms of Parkinson’s using his own cells.

Follow us on Instagram @docvsparkinsons as we will be updating and communication how the clinical trials are proceeding on Instagram mostly. And if the FDA requires more trials we will post how to be considered on Instagram."

[Bolt_Upright in reply to JAS9]

Thanks! I will be signing up for Instagram today!

[JAS9 in reply to Bolt_Upright]

There's not a lot of new info there as of 2 days ago, but hopefully they'll be having more info as the clinical trials really get going.

[Despe in reply to JAS9]

JAS,

Thanks for the update. Fantastic and promising news!!

[JAS9 in reply to Despe]

I'll be checking Instagram at least once a week and I will post any major news here for those who don't want to bother with an Instagram account.

[Despe in reply to JAS9]

Hi JAS!

Long time ago, before hubby was diagnosed and being Cyber Security Officer/Manager for the Air Force and then Army, he was against any social media. Following his expert advice, we never created a social media account. It's not that we don't want to bother, but it's for reasons of SECURITY. Still "they" know every minute of our private life.

Would appreciate anything you can share with us.

[JAS9 in reply to JAS9]

Update on Doc from Instagram

Doc is getting better. And he is keeping his promise of helping others. Still a long road to go but Doc is determined to... more

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docvsparkinsons @henridanjou hi Henry. Doc, at the beginning was trying to find time for everyone, but emotionally it was draining because he wants to go faster, he wants to treat now but understandably he is waiting the FDA process and clinical trials out. This is Brent Deal the movies director. Keep following I will update every couple of weeks how the clinical trial is going once it’s approved. You’re young and it’s early, Doc is so hoping he gets to treat you someday. Rooting for you.

docvsparkinsons @henridanjou click on link in bio and watch docs Parkinson’s in 6 minutes. Or find it on YouTube. Essentially the cells... more

[BrentDeal in reply to JAS9]

Hi JAS9 it's Brent Deal again. I'm going to start commenting on all these posts as it's very important that we are completely honest with everyone strickened with this awful disease. After a few set backs Doc and Kwang-Soo are "very close" to getting FDA approval to start clinicals.Doc continues to improve- scientifically it's proven.. as his friend I can see it first hand. As for the FDA, Doc is a tremendous force to be reckoned with- Right now his full focus and anger is pointed at the FDA for not moving as fast as he wants them to.

[kevowpd in reply to BrentDeal]

It might be best to just do a new thread outlining whatever info you wish to communicate.

[JAS9 in reply to Hidden]

This is another response I got from a different email address. It's from McLean Hospital which is where doc had his surgery performed and who he is working with:

"Thank you for your interest in our Parkinson’s disease research. We are optimistic about the future potential of cell therapy for Parkinson’s, but it is important to understand that this work is still at a very early stage and that much remains to be done. We are currently preparing for a clinical trial to determine how safe and effective the procedure is. It will likely be some years before we have this information.

If you are interested in helping advance this therapy, we are currently enrolling for a study aimed at studying the performance of the cell manufacturing protocol. The study involves providing a sample of skin cells and annual trips to Boston for clinical evaluation, but does not involve transplantation of the cells into the brain. If you live near Boston and are interested in learning more about this study, please reply to this email with a phone number and the best time to call you between 8 a.m. and 5 p.m. Monday - Friday.

Please consider visiting this McLean Hospital website (parkinsonscelltherapy.org/) for more information on the science behind this cell therapy treatment. If you are interested in learning more about currently available treatments for Parkinson’s disease, please visit the Mass General Hospital Neurology or Neurosurgery website (massgeneral.org/neurosurger... . For inquiries, please contact us at the MGH PD Cell Therapy information line at 617-749-2551 or email us at [e-mail].

Thank you

MGH-McClean PD Cell Therapy Team"

[BrentDeal in reply to JAS9]

you are a force to be reckoned with JAS9. message me on instagram- @docvsparkinsons I will tell you everything I know and you can post everywhere you want.

[Erniediaz1018]

Thank you, very encouraging

[Gcf51]

I wonder, is this the same kind of treatment as shown on 60 minutes for Sickle Cell. They took Stem cells, recoded the defective gene and put them back.

[JAS9]

The very latest, more detailed update:

Doc continues to get better slowly- he's off half his meds(!) and he's much more active than he was prior to surgery.

He's skiing, boxing and spearfishing again- all things he had effectively given up.

One interesting tidbit- he received 5 million cells during the treatment. In hindsight, maybe not enough to improve as fast as he wanted to.

The next 10 in the clinical trials will receive 25 million cells.

Doc would like to have more cells implanted into his head - but the FDA made him sign a contract before he became patient 1, agreeing that he would not get more because he is the Guinea Pig and is under constant observation and scrutiny.

Every time he gets tested he has to come off his meds- which is getting easier for him- but is still a chore every time he does it.

The next 10 subjects are really close to having final approval. It's been a long back and forth with the FDA.

Sadly, when the team tried to start this clinical almost two years ago, they had a problem immediately with the quality of the skin cells taken from the patients. Once they were converted to iPSC cells they weren't as 'pure' as Doc's cells had been.

Unfortunately, it took Kwang-Soo 2 years to figure out the problem.

Fortunately, he has figured it out and a couple of weeks ago the FDA said they are 'approved' to begin again based on a couple of clarifications... which should take a couple of months for Doc and Kwang-Soo to satisfy.

So we believe clinical trials will start again in 4 months- and it should go fast-

they'll take the cells, put them in the brains of the patients and in 6 months the results should show up in cat scans and then Doc and the team will be off and running with whatever the FDA challenges them with at that stage.

[Bolt_Upright in reply to JAS9]

That is an awesome update! Thanks!

[JAS9]

it's interesting to see what goes on "behind the curtain" during this kind of clinical trial. Brent also said that Doc and the entire team are confident despite the delay. But they also don't want to disappoint a lot of people if something should block their progress. "It's still a long road".